Ku80 is highly expressed in lung adenocarcinoma and promotes cisplatin resistance

Ku80 is highly expressed in lung adenocarcinoma and promotes cisplatin resistance

<p>Abstract</p> <p>Background</p> <p>Ku80 is crucially implicated in DNA repair, apoptosis, and chemoresistance. In this study, we aimed to assess the expression of Ku80 in clinical lung adenocarcinoma specimens, and investigate its role in the regulation of cisplatin s...

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Bibliographic Details
Main Authors: Ma Qingshan, Li Ping, Xu Minyu, Yin Jinzhi, Su Zhenzhong, Li Wei, Zhang Jie
Format: Article
Language:English
Published: BMC 2012-11-01
Series:Journal of Experimental & Clinical Cancer Research
Subjects:
Ku80
Lung cancer
Chemotherapy
siRNA
Cisplatin
Online Access:http://www.jeccr.com/content/31/1/99

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