Viscosupplementation in the Therapy for Osteoarthritic Knee
Osteoarthritis (OA) is a degenerative disease that is spreading worldwide due to an aging population. This is not simply a disease caused by worn out joints, but a complex disease accompanied by various mechanisms such as inflammatory reactions. Among various joints, knee joints show degenerative ch...
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| Format: | Article |
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MDPI AG
2021-12-01
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| Series: | Applied Sciences |
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| Online Access: | https://www.mdpi.com/2076-3417/11/24/11621 |
| _version_ | 1797506820143579136 |
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| author | Junghyun Park Hue Jung Park Min Cheol Rho Jin Joo |
| author_facet | Junghyun Park Hue Jung Park Min Cheol Rho Jin Joo |
| author_sort | Junghyun Park |
| collection | DOAJ |
| description | Osteoarthritis (OA) is a degenerative disease that is spreading worldwide due to an aging population. This is not simply a disease caused by worn out joints, but a complex disease accompanied by various mechanisms such as inflammatory reactions. Among various joints, knee joints show degenerative changes earlier than other joints because they carry most of the weight load, causing social-economic problems. In the case of OA of the knee that does not respond to relatively simple conservative treatments such as physical therapy or medication, intra-articular injection is preferred. However, intra-articular injection drugs have limited effectiveness and uncertainties. There are several intra-articular viscous supplement drugs such as hyaluronic acid. Tissue regeneration active materials such as polydeoxyribonucleotide and polynucleotide are also newly used. The objective of this paper was to compare effects of intra-articular supplementation drugs used for degenerative arthritis of the knee. |
| first_indexed | 2024-03-10T04:37:54Z |
| format | Article |
| id | doaj.art-b592802382f04e678bc739e588f257e1 |
| institution | Directory Open Access Journal |
| issn | 2076-3417 |
| language | English |
| last_indexed | 2024-03-10T04:37:54Z |
| publishDate | 2021-12-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Applied Sciences |
| spelling | doaj.art-b592802382f04e678bc739e588f257e12023-11-23T03:35:45ZengMDPI AGApplied Sciences2076-34172021-12-0111241162110.3390/app112411621Viscosupplementation in the Therapy for Osteoarthritic KneeJunghyun Park0Hue Jung Park1Min Cheol Rho2Jin Joo3Department of Anesthesiology and Pain Medicine, Incheon St. Mary’s Hospital, College of Medicine, The Catholic University of Korea, Incheon 21431, KoreaDepartment of Anesthesiology and Pain Medicine, Seoul St. Mary’s Hospital, College of Medicine, The Catholic University of Korea, Seoul 06591, KoreaDepartment of Anesthesiology and Pain Medicine, Seoul St. Mary’s Hospital, College of Medicine, The Catholic University of Korea, Seoul 06591, KoreaDepartment of Anesthesiology and Pain Medicine, Seoul St. Mary’s Hospital, College of Medicine, The Catholic University of Korea, Seoul 06591, KoreaOsteoarthritis (OA) is a degenerative disease that is spreading worldwide due to an aging population. This is not simply a disease caused by worn out joints, but a complex disease accompanied by various mechanisms such as inflammatory reactions. Among various joints, knee joints show degenerative changes earlier than other joints because they carry most of the weight load, causing social-economic problems. In the case of OA of the knee that does not respond to relatively simple conservative treatments such as physical therapy or medication, intra-articular injection is preferred. However, intra-articular injection drugs have limited effectiveness and uncertainties. There are several intra-articular viscous supplement drugs such as hyaluronic acid. Tissue regeneration active materials such as polydeoxyribonucleotide and polynucleotide are also newly used. The objective of this paper was to compare effects of intra-articular supplementation drugs used for degenerative arthritis of the knee.https://www.mdpi.com/2076-3417/11/24/11621osteoarthritisknee viscosupplementhyaluronic acidcross-linked hyaluronic acidpolydeoxyribonucleotidepolynucleotide |
| spellingShingle | Junghyun Park Hue Jung Park Min Cheol Rho Jin Joo Viscosupplementation in the Therapy for Osteoarthritic Knee Applied Sciences osteoarthritis knee viscosupplement hyaluronic acid cross-linked hyaluronic acid polydeoxyribonucleotide polynucleotide |
| title | Viscosupplementation in the Therapy for Osteoarthritic Knee |
| title_full | Viscosupplementation in the Therapy for Osteoarthritic Knee |
| title_fullStr | Viscosupplementation in the Therapy for Osteoarthritic Knee |
| title_full_unstemmed | Viscosupplementation in the Therapy for Osteoarthritic Knee |
| title_short | Viscosupplementation in the Therapy for Osteoarthritic Knee |
| title_sort | viscosupplementation in the therapy for osteoarthritic knee |
| topic | osteoarthritis knee viscosupplement hyaluronic acid cross-linked hyaluronic acid polydeoxyribonucleotide polynucleotide |
| url | https://www.mdpi.com/2076-3417/11/24/11621 |
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