Isolinderalactone Induces Apoptosis, Autophagy, Cell Cycle Arrest and MAPK Activation through ROS–Mediated Signaling in Colorectal Cancer Cell Lines

Isolinderalactone Induces Apoptosis, Autophagy, Cell Cycle Arrest and MAPK Activation through ROS–Mediated Signaling in Colorectal Cancer Cell Lines

Colorectal cancer (CRC) is one of the most common malignancies worldwide. Isolinderalactone (ILL), a sesquiterpene isolated from the root extract of <i>Lindera aggregata</i>, has been reported to exhibit anti–proliferative and anti–metastatic activities in various cancer cell lines. Howe...

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Bibliographic Details
Main Authors:	Jith-Shyan Chen, Sheng-Chun Chiu, Sung-Ying Huang, Shu-Fang Chang, Kuan-Fu Liao
Format:	Article
Language:	English
Published:	MDPI AG 2023-09-01
Series:	International Journal of Molecular Sciences
Subjects:	colorectal cancer isolinderalactone apoptosis autophagy G2/M arrest ROS
Online Access:	https://www.mdpi.com/1422-0067/24/18/14246

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