History of Delirium Tremens in AUD Patients in Treatment: Relationship to AUD Severity and Other Factors
Jørgen G Bramness,1– 3 Susmita Pandey,1 Jenny Skumsnes Moe,1,3 Helge Toft,1,4 Lars Lien,1,4 Ingeborg Bolstad1,4 1Norwegian National Advisory Unit on Concurrent Substance Abuse and Mental Health Disorders, Innlandet Hospital Trust, Brumunddal, Norway; 2Norwegian Institute of Public Health, Department...
| Main Authors: | , , , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Dove Medical Press
2022-09-01
|
| Series: | Substance Abuse and Rehabilitation |
| Subjects: | |
| Online Access: | https://www.dovepress.com/history-of-delirium-tremens-in-aud-patients-in-treatment-relationship--peer-reviewed-fulltext-article-SAR |
| _version_ | 1818056119292002304 |
|---|---|
| author | Bramness JG Pandey S Moe JS Toft H Lien L Bolstad I |
| author_facet | Bramness JG Pandey S Moe JS Toft H Lien L Bolstad I |
| author_sort | Bramness JG |
| collection | DOAJ |
| description | Jørgen G Bramness,1– 3 Susmita Pandey,1 Jenny Skumsnes Moe,1,3 Helge Toft,1,4 Lars Lien,1,4 Ingeborg Bolstad1,4 1Norwegian National Advisory Unit on Concurrent Substance Abuse and Mental Health Disorders, Innlandet Hospital Trust, Brumunddal, Norway; 2Norwegian Institute of Public Health, Department of Alcohol, Tobacco and Drugs, Oslo, Norway; 3Institute Clinical of Medicine, UiT – The Arctic University of Norway, Tromsø, Norway; 4Department of Health Studies, Inland Norway University of Applied Sciences, Elverum, NorwayCorrespondence: Jørgen G Bramness, Norwegian Institute of Public Health, P.O.Box 222, Oslo, 0213, Norway, Email jobr@fhi.noIntroduction: Delirium tremens (DT) occurs after stopping prolonged, high alcohol intake and may be life-threatening if untreated. We need to know about clinical correlates of DT in order to provide the best clinical care.Methods: At admission to inpatient treatment a cohort of 114 alcohol use disorder (AUD) patients were interviewed and examined concerning psychiatric diagnosis and symptoms, trauma experiences and alcohol related measures and if they had experienced DT.Results: Twenty-four percent of the patients reported a life-time experience of DT. These patients were predominantly males and had lower educational level. More of the patients in the DT than the non-DT group reported at least one suicide attempt, were diagnosed with PTSD, and dropped out of treatment. Also, having parents with alcohol problems was more common among these patients, and they reported a longer duration of problematic drinking and a higher number of drinks needed to feel an effect of drinking. In the multivariable adjusted analysis only a diagnosis of PTSD (OR=5.71; 95% confidence interval (CI): 1.34– 24.31) and duration of problematic drinking with a 6% increase in risk for every year (OR=1.06; 95% CI: 1.01– 1.11) remained significant risk factors for having DT experience.Discussion and conclusion: Having experienced DT was more prevalent in the current investigation than in earlier studies. Patients that had experienced DT seemed to have more serious AUD, especially signified by a longer duration of drinking. These patients seemed to have many clinical disadvantages including more drop-out and higher suicide rate. PTSD could be a risk factor for DT but may also follow the DT experience.Keywords: alcohol use disorder, delirium tremens, treatment, PTSD |
| first_indexed | 2024-12-10T12:23:46Z |
| format | Article |
| id | doaj.art-b59790058f184046b61801604a2f7cd2 |
| institution | Directory Open Access Journal |
| issn | 1179-8467 |
| language | English |
| last_indexed | 2024-12-10T12:23:46Z |
| publishDate | 2022-09-01 |
| publisher | Dove Medical Press |
| record_format | Article |
| series | Substance Abuse and Rehabilitation |
| spelling | doaj.art-b59790058f184046b61801604a2f7cd22022-12-22T01:49:01ZengDove Medical PressSubstance Abuse and Rehabilitation1179-84672022-09-01Volume 13657278185History of Delirium Tremens in AUD Patients in Treatment: Relationship to AUD Severity and Other FactorsBramness JGPandey SMoe JSToft HLien LBolstad IJørgen G Bramness,1– 3 Susmita Pandey,1 Jenny Skumsnes Moe,1,3 Helge Toft,1,4 Lars Lien,1,4 Ingeborg Bolstad1,4 1Norwegian National Advisory Unit on Concurrent Substance Abuse and Mental Health Disorders, Innlandet Hospital Trust, Brumunddal, Norway; 2Norwegian Institute of Public Health, Department of Alcohol, Tobacco and Drugs, Oslo, Norway; 3Institute Clinical of Medicine, UiT – The Arctic University of Norway, Tromsø, Norway; 4Department of Health Studies, Inland Norway University of Applied Sciences, Elverum, NorwayCorrespondence: Jørgen G Bramness, Norwegian Institute of Public Health, P.O.Box 222, Oslo, 0213, Norway, Email jobr@fhi.noIntroduction: Delirium tremens (DT) occurs after stopping prolonged, high alcohol intake and may be life-threatening if untreated. We need to know about clinical correlates of DT in order to provide the best clinical care.Methods: At admission to inpatient treatment a cohort of 114 alcohol use disorder (AUD) patients were interviewed and examined concerning psychiatric diagnosis and symptoms, trauma experiences and alcohol related measures and if they had experienced DT.Results: Twenty-four percent of the patients reported a life-time experience of DT. These patients were predominantly males and had lower educational level. More of the patients in the DT than the non-DT group reported at least one suicide attempt, were diagnosed with PTSD, and dropped out of treatment. Also, having parents with alcohol problems was more common among these patients, and they reported a longer duration of problematic drinking and a higher number of drinks needed to feel an effect of drinking. In the multivariable adjusted analysis only a diagnosis of PTSD (OR=5.71; 95% confidence interval (CI): 1.34– 24.31) and duration of problematic drinking with a 6% increase in risk for every year (OR=1.06; 95% CI: 1.01– 1.11) remained significant risk factors for having DT experience.Discussion and conclusion: Having experienced DT was more prevalent in the current investigation than in earlier studies. Patients that had experienced DT seemed to have more serious AUD, especially signified by a longer duration of drinking. These patients seemed to have many clinical disadvantages including more drop-out and higher suicide rate. PTSD could be a risk factor for DT but may also follow the DT experience.Keywords: alcohol use disorder, delirium tremens, treatment, PTSDhttps://www.dovepress.com/history-of-delirium-tremens-in-aud-patients-in-treatment-relationship--peer-reviewed-fulltext-article-SARalcohol use disorderdelirium tremenstreatmentptsd |
| spellingShingle | Bramness JG Pandey S Moe JS Toft H Lien L Bolstad I History of Delirium Tremens in AUD Patients in Treatment: Relationship to AUD Severity and Other Factors Substance Abuse and Rehabilitation alcohol use disorder delirium tremens treatment ptsd |
| title | History of Delirium Tremens in AUD Patients in Treatment: Relationship to AUD Severity and Other Factors |
| title_full | History of Delirium Tremens in AUD Patients in Treatment: Relationship to AUD Severity and Other Factors |
| title_fullStr | History of Delirium Tremens in AUD Patients in Treatment: Relationship to AUD Severity and Other Factors |
| title_full_unstemmed | History of Delirium Tremens in AUD Patients in Treatment: Relationship to AUD Severity and Other Factors |
| title_short | History of Delirium Tremens in AUD Patients in Treatment: Relationship to AUD Severity and Other Factors |
| title_sort | history of delirium tremens in aud patients in treatment relationship to aud severity and other factors |
| topic | alcohol use disorder delirium tremens treatment ptsd |
| url | https://www.dovepress.com/history-of-delirium-tremens-in-aud-patients-in-treatment-relationship--peer-reviewed-fulltext-article-SAR |
| work_keys_str_mv | AT bramnessjg historyofdeliriumtremensinaudpatientsintreatmentrelationshiptoaudseverityandotherfactors AT pandeys historyofdeliriumtremensinaudpatientsintreatmentrelationshiptoaudseverityandotherfactors AT moejs historyofdeliriumtremensinaudpatientsintreatmentrelationshiptoaudseverityandotherfactors AT tofth historyofdeliriumtremensinaudpatientsintreatmentrelationshiptoaudseverityandotherfactors AT lienl historyofdeliriumtremensinaudpatientsintreatmentrelationshiptoaudseverityandotherfactors AT bolstadi historyofdeliriumtremensinaudpatientsintreatmentrelationshiptoaudseverityandotherfactors |