BPOZ-2 is a negative regulator of the NLPR3 inflammasome contributing to SARS-CoV-2-induced hyperinflammation

BPOZ-2 is a negative regulator of the NLPR3 inflammasome contributing to SARS-CoV-2-induced hyperinflammation

IntroductionInflammation play important roles in the initiation and progression of acute lung injury (ALI), acute respiratory distress syndrome (ARDS), septic shock, clotting dysfunction, or even death associated with SARS-CoV-2 infection. However, the pathogenic mechanisms underlying SARS-CoV-2-ind...

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Bibliographic Details
Main Authors: Jingfei Li, Haotian Lin, Tinghui Fan, Linfei Huang, Xinyong Zhang, Yanhong Tai, Yi Fang, Qihong Li, Ruzhou Zhao, Penghao Wang, Li Zhou, Luming Wan, Yuhua Wu, Hui Zhong, Congwen Wei, Xiaopan Yang
Format: Article
Language:English
Published: Frontiers Media S.A. 2023-03-01
Series:Frontiers in Cellular and Infection Microbiology
Subjects:
BPOZ-2
NLPR3
inflammasome
SARS-CoV-2
hyperinflammation
Online Access:https://www.frontiersin.org/articles/10.3389/fcimb.2023.1134511/full

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