Pain syndrome in rheumatoid arthritis
Subjects and methods. One hundred and eighty-three patients with valid rheumatoid arthritis (RA) were examined to study the specific fea tures of chronic pain syndrome. The DN4 neuropathic pain diagnostic questionnaire was used to divide all the patients into 2 gro...
| Main Authors: | , , |
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| Format: | Article |
| Language: | Russian |
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IMA PRESS LLC
2011-12-01
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| Series: | Научно-практическая ревматология |
| Subjects: | |
| Online Access: | https://rsp.mediar-press.net/rsp/article/view/655 |
| _version_ | 1826556154112638976 |
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| author | Ekaterina Sergeyevna Filatova V V Alekseyev Sh F Erdes |
| author_facet | Ekaterina Sergeyevna Filatova V V Alekseyev Sh F Erdes |
| author_sort | Ekaterina Sergeyevna Filatova |
| collection | DOAJ |
| description | Subjects and methods. One hundred and eighty-three patients with valid rheumatoid arthritis (RA) were examined to study the specific fea tures of chronic pain syndrome. The DN4 neuropathic pain diagnostic questionnaire was used to divide all the patients into 2 groups: 1) 78 patients with the neuropathic component of pain (NCP) and 2) 105 patients without the latter. Results. A clinical neurological examination could reveal peripheral nervous system lesion in 96% of Group 1 patients and in 4% of Group 2 ones. The patients with NCP were ascertained to be older, they were longer ill with RA, had higher clinical, X-ray stages and functional class, as well as higher pain intensity. However, no differences were found between the two groups in the values of disease activity (DAS 28) and erythrocyte sedimentation rate. There was a high rate (71%) of depressive disorders, the prevalence and degree of which in RA patients were determined by the characteristics of disease severity and did not depend on the presence of NCP. Discussion. The performed study demonstrated that, along with an obligate nociceptive mechanism, the patients with RA had neurogenic and psychogenic components of pain in 43 and 71% of cases, respectively. Consequently, chronic pain syndrome in RA is commonly mixed and both the activity of the inflammatory process and the magnitude of neurogenic and psychogenic components should be borne in mind for optimal pain control. |
| first_indexed | 2024-04-09T22:26:31Z |
| format | Article |
| id | doaj.art-b5982445ac0d46afbeebb968ec05dc5c |
| institution | Directory Open Access Journal |
| issn | 1995-4484 1995-4492 |
| language | Russian |
| last_indexed | 2025-03-14T08:08:11Z |
| publishDate | 2011-12-01 |
| publisher | IMA PRESS LLC |
| record_format | Article |
| series | Научно-практическая ревматология |
| spelling | doaj.art-b5982445ac0d46afbeebb968ec05dc5c2025-03-02T13:23:35ZrusIMA PRESS LLCНаучно-практическая ревматология1995-44841995-44922011-12-01496323510.14412/1995-4484-2011-517595Pain syndrome in rheumatoid arthritisEkaterina Sergeyevna FilatovaV V AlekseyevSh F ErdesSubjects and methods. One hundred and eighty-three patients with valid rheumatoid arthritis (RA) were examined to study the specific fea tures of chronic pain syndrome. The DN4 neuropathic pain diagnostic questionnaire was used to divide all the patients into 2 groups: 1) 78 patients with the neuropathic component of pain (NCP) and 2) 105 patients without the latter. Results. A clinical neurological examination could reveal peripheral nervous system lesion in 96% of Group 1 patients and in 4% of Group 2 ones. The patients with NCP were ascertained to be older, they were longer ill with RA, had higher clinical, X-ray stages and functional class, as well as higher pain intensity. However, no differences were found between the two groups in the values of disease activity (DAS 28) and erythrocyte sedimentation rate. There was a high rate (71%) of depressive disorders, the prevalence and degree of which in RA patients were determined by the characteristics of disease severity and did not depend on the presence of NCP. Discussion. The performed study demonstrated that, along with an obligate nociceptive mechanism, the patients with RA had neurogenic and psychogenic components of pain in 43 and 71% of cases, respectively. Consequently, chronic pain syndrome in RA is commonly mixed and both the activity of the inflammatory process and the magnitude of neurogenic and psychogenic components should be borne in mind for optimal pain control.https://rsp.mediar-press.net/rsp/article/view/655rheumatoid arthritischronic pain syndromeneuropathic and nociceptive painanxiety-and-depressive disorders |
| spellingShingle | Ekaterina Sergeyevna Filatova V V Alekseyev Sh F Erdes Pain syndrome in rheumatoid arthritis Научно-практическая ревматология rheumatoid arthritis chronic pain syndrome neuropathic and nociceptive pain anxiety-and-depressive disorders |
| title | Pain syndrome in rheumatoid arthritis |
| title_full | Pain syndrome in rheumatoid arthritis |
| title_fullStr | Pain syndrome in rheumatoid arthritis |
| title_full_unstemmed | Pain syndrome in rheumatoid arthritis |
| title_short | Pain syndrome in rheumatoid arthritis |
| title_sort | pain syndrome in rheumatoid arthritis |
| topic | rheumatoid arthritis chronic pain syndrome neuropathic and nociceptive pain anxiety-and-depressive disorders |
| url | https://rsp.mediar-press.net/rsp/article/view/655 |
| work_keys_str_mv | AT ekaterinasergeyevnafilatova painsyndromeinrheumatoidarthritis AT vvalekseyev painsyndromeinrheumatoidarthritis AT shferdes painsyndromeinrheumatoidarthritis |