Synchronous Sporadic Gastrointestinal Stromal Tumors in the Stomach and Jejunum: Report of a Case

This report describes a patient with synchronous sporadic gastrointestinal stromal tumors (GISTs) in the stomach and jejunum. A 71-year-old Japanese male presented with a 2-year history of occasional melena and general fatigue. Computed tomography of the abdomen demonstrated an enhanced extramural g...

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Main Authors: Yoshifumi Nakayama, Kouji Kadowaki, Aiichirou Higure, Masanori Hisaoka, Koji Yamaguchi
Format: Article
Language:English
Published: Karger Publishers 2013-03-01
Series:Case Reports in Gastroenterology
Subjects:
Online Access:http://www.karger.com/Article/FullText/348754
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author Yoshifumi Nakayama
Kouji Kadowaki
Aiichirou Higure
Masanori Hisaoka
Koji Yamaguchi
author_facet Yoshifumi Nakayama
Kouji Kadowaki
Aiichirou Higure
Masanori Hisaoka
Koji Yamaguchi
author_sort Yoshifumi Nakayama
collection DOAJ
description This report describes a patient with synchronous sporadic gastrointestinal stromal tumors (GISTs) in the stomach and jejunum. A 71-year-old Japanese male presented with a 2-year history of occasional melena and general fatigue. Computed tomography of the abdomen demonstrated an enhanced extramural gastric tumor, 4 cm in diameter. Endoscopic examination revealed a jejunal submucosal tumor. He was referred to the surgical outpatient clinic for surgical treatment of an extramural gastric tumor and a jejunal submucosal tumor. Laparotomy allowed the identification of a nut-sized extramural tumor at the stomach and a thumb's head-sized tumor on the jejunum. Partial resections of the stomach and jejunum were performed. Histopathological and immunohistochemical examination revealed that these tumors were GISTs. Although no molecular analysis was performed, the immunohistochemical staining patterns of these two tumors were different from each other. Therefore, the final diagnosis was synchronous sporadic GISTs in the stomach and jejunum. This patient has survived without recurrence for approximately 12 years since complete resection.
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spelling doaj.art-b59827d599ab4a6b9beba626ff63e9522022-12-21T21:53:01ZengKarger PublishersCase Reports in Gastroenterology1662-06312013-03-0171697410.1159/000348754348754Synchronous Sporadic Gastrointestinal Stromal Tumors in the Stomach and Jejunum: Report of a CaseYoshifumi NakayamaKouji KadowakiAiichirou HigureMasanori HisaokaKoji YamaguchiThis report describes a patient with synchronous sporadic gastrointestinal stromal tumors (GISTs) in the stomach and jejunum. A 71-year-old Japanese male presented with a 2-year history of occasional melena and general fatigue. Computed tomography of the abdomen demonstrated an enhanced extramural gastric tumor, 4 cm in diameter. Endoscopic examination revealed a jejunal submucosal tumor. He was referred to the surgical outpatient clinic for surgical treatment of an extramural gastric tumor and a jejunal submucosal tumor. Laparotomy allowed the identification of a nut-sized extramural tumor at the stomach and a thumb's head-sized tumor on the jejunum. Partial resections of the stomach and jejunum were performed. Histopathological and immunohistochemical examination revealed that these tumors were GISTs. Although no molecular analysis was performed, the immunohistochemical staining patterns of these two tumors were different from each other. Therefore, the final diagnosis was synchronous sporadic GISTs in the stomach and jejunum. This patient has survived without recurrence for approximately 12 years since complete resection.http://www.karger.com/Article/FullText/348754SynchronousStomachJejunumGastrointestinal stromal tumorSporadic
spellingShingle Yoshifumi Nakayama
Kouji Kadowaki
Aiichirou Higure
Masanori Hisaoka
Koji Yamaguchi
Synchronous Sporadic Gastrointestinal Stromal Tumors in the Stomach and Jejunum: Report of a Case
Case Reports in Gastroenterology
Synchronous
Stomach
Jejunum
Gastrointestinal stromal tumor
Sporadic
title Synchronous Sporadic Gastrointestinal Stromal Tumors in the Stomach and Jejunum: Report of a Case
title_full Synchronous Sporadic Gastrointestinal Stromal Tumors in the Stomach and Jejunum: Report of a Case
title_fullStr Synchronous Sporadic Gastrointestinal Stromal Tumors in the Stomach and Jejunum: Report of a Case
title_full_unstemmed Synchronous Sporadic Gastrointestinal Stromal Tumors in the Stomach and Jejunum: Report of a Case
title_short Synchronous Sporadic Gastrointestinal Stromal Tumors in the Stomach and Jejunum: Report of a Case
title_sort synchronous sporadic gastrointestinal stromal tumors in the stomach and jejunum report of a case
topic Synchronous
Stomach
Jejunum
Gastrointestinal stromal tumor
Sporadic
url http://www.karger.com/Article/FullText/348754
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