Treatment of Systemic Sclerosis Associated Interstitial Lung Disease
Systemic sclerosis (SSc) is a systemic connective tissue disorder characterized by progressive skin and visceral organ fibrosis, vasculopathy, and immune dysregulation. Interstitial lung disease (ILD) is a common manifestation and major contributor to morbidity and mortality. Immunosuppression is us...
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| Format: | Article |
| Language: | English |
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World Scientific Publishing
2020-12-01
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| Series: | Journal of Clinical Rheumatology and Immunology |
| Subjects: | |
| Online Access: | http://www.worldscientific.com/doi/epdf/10.1142/S2661341720300050 |
| _version_ | 1818459361547124736 |
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| author | Iris Yan Ki Tang So Ho |
| author_facet | Iris Yan Ki Tang So Ho |
| author_sort | Iris Yan Ki Tang |
| collection | DOAJ |
| description | Systemic sclerosis (SSc) is a systemic connective tissue disorder characterized by progressive skin and visceral organ fibrosis, vasculopathy, and immune dysregulation. Interstitial lung disease (ILD) is a common manifestation and major contributor to morbidity and mortality. Immunosuppression is usually indicated for extensive or progressive SSc-ILD. Recently, antifibrotic and biological therapies have been shown to be efficacious in treating SSc-ILD in various studies. In this article, we will descriptively review the latest evidence on the treatment of SSc-ILD. |
| first_indexed | 2024-12-14T23:13:08Z |
| format | Article |
| id | doaj.art-b59b1b8ec9854e33b2fb3c827031598b |
| institution | Directory Open Access Journal |
| issn | 2661-3417 2661-3425 |
| language | English |
| last_indexed | 2024-12-14T23:13:08Z |
| publishDate | 2020-12-01 |
| publisher | World Scientific Publishing |
| record_format | Article |
| series | Journal of Clinical Rheumatology and Immunology |
| spelling | doaj.art-b59b1b8ec9854e33b2fb3c827031598b2022-12-21T22:44:09ZengWorld Scientific PublishingJournal of Clinical Rheumatology and Immunology2661-34172661-34252020-12-01202566410.1142/S266134172030005010.1142/S2661341720300050Treatment of Systemic Sclerosis Associated Interstitial Lung DiseaseIris Yan Ki Tang0So Ho1Department of Medicine and Geriatrics, Kwong Wah Hospital, Hong KongDepartment of Medicine and Therapeutics, The Chinese University of Hong Kong, Hong KongSystemic sclerosis (SSc) is a systemic connective tissue disorder characterized by progressive skin and visceral organ fibrosis, vasculopathy, and immune dysregulation. Interstitial lung disease (ILD) is a common manifestation and major contributor to morbidity and mortality. Immunosuppression is usually indicated for extensive or progressive SSc-ILD. Recently, antifibrotic and biological therapies have been shown to be efficacious in treating SSc-ILD in various studies. In this article, we will descriptively review the latest evidence on the treatment of SSc-ILD.http://www.worldscientific.com/doi/epdf/10.1142/S2661341720300050systemic sclerosissclerodermainterstitial lung diseasepulmonary fibrosislung disease |
| spellingShingle | Iris Yan Ki Tang So Ho Treatment of Systemic Sclerosis Associated Interstitial Lung Disease Journal of Clinical Rheumatology and Immunology systemic sclerosis scleroderma interstitial lung disease pulmonary fibrosis lung disease |
| title | Treatment of Systemic Sclerosis Associated Interstitial Lung Disease |
| title_full | Treatment of Systemic Sclerosis Associated Interstitial Lung Disease |
| title_fullStr | Treatment of Systemic Sclerosis Associated Interstitial Lung Disease |
| title_full_unstemmed | Treatment of Systemic Sclerosis Associated Interstitial Lung Disease |
| title_short | Treatment of Systemic Sclerosis Associated Interstitial Lung Disease |
| title_sort | treatment of systemic sclerosis associated interstitial lung disease |
| topic | systemic sclerosis scleroderma interstitial lung disease pulmonary fibrosis lung disease |
| url | http://www.worldscientific.com/doi/epdf/10.1142/S2661341720300050 |
| work_keys_str_mv | AT irisyankitang treatmentofsystemicsclerosisassociatedinterstitiallungdisease AT soho treatmentofsystemicsclerosisassociatedinterstitiallungdisease |