Sex Differences, Estrogen Metabolism and Signaling in the Development of Pulmonary Arterial Hypertension

Sex Differences, Estrogen Metabolism and Signaling in the Development of Pulmonary Arterial Hypertension

Pulmonary arterial hypertension (PAH) is a complex and devastating disease with a poor long-term prognosis. While women are at increased risk for developing PAH, they exhibit superior right heart function and higher survival rates than men. Susceptibility to disease risk in PAH has been attributed,...

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Bibliographic Details
Main Authors: Yanan Sun, Shreya Sangam, Qiang Guo, Jian Wang, Haiyang Tang, Stephen M. Black, Ankit A. Desai
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-09-01
Series:Frontiers in Cardiovascular Medicine
Subjects:
pulmonary arterial hypertension
estrogen paradox
estrogen metabolism
estrogen receptors
pulmonary hypertension
Online Access:https://www.frontiersin.org/articles/10.3389/fcvm.2021.719058/full

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