Imidacloprid Impairs Glutamatergic Synaptic Plasticity and Desensitizes Mechanosensitive, Nociceptive, and Photogenic Response of <i>Drosophila melanogaster</i> by Mediating Oxidative Stress, Which Could Be Rescued by Osthole

Imidacloprid Impairs Glutamatergic Synaptic Plasticity and Desensitizes Mechanosensitive, Nociceptive, and Photogenic Response of <i>Drosophila melanogaster</i> by Mediating Oxidative Stress, Which Could Be Rescued by Osthole

Background: Imidacloprid (IMD) is a widely used neonicotinoid-targeting insect nicotine acetylcholine receptors (nAChRs). However, off-target effects raise environmental concerns, including the IMD’s impairment of the memory of honeybees and rodents. Although the down-regulation of inotropic glutama...

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Bibliographic Details
Main Authors: Chuan-Hsiu Liu, Mei-Ying Chen, Jack Cheng, Tsai-Ni Chuang, Hsin-Ping Liu, Wei-Yong Lin
Format: Article
Language:English
Published: MDPI AG 2022-09-01
Series:International Journal of Molecular Sciences
Subjects:
Imidacloprid
glutamate receptor
neuroplasticity
<i>Drosophila melanogaster</i>
Online Access:https://www.mdpi.com/1422-0067/23/17/10181

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