Silver-decorated gel-shell nanobeads: physicochemical characterization and evaluation of antibacterial properties
We report on the synthesis of composite nanobeads with antibacterial properties. The particles consist of polystyrene cores that are surrounded by sulfonic gel shells with embedded silver nanoparticles. The nanocomposite beads are prepared by sulfonation of polystyrene particles followed by accumula...
| Main Authors: | , , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Beilstein-Institut
2020-04-01
|
| Series: | Beilstein Journal of Nanotechnology |
| Subjects: | |
| Online Access: | https://doi.org/10.3762/bjnano.11.49 |
| _version_ | 1819229649883889664 |
|---|---|
| author | Marta Bartel Katarzyna Markowska Marcin Strawski Krystyna Wolska Maciej Mazur |
| author_facet | Marta Bartel Katarzyna Markowska Marcin Strawski Krystyna Wolska Maciej Mazur |
| author_sort | Marta Bartel |
| collection | DOAJ |
| description | We report on the synthesis of composite nanobeads with antibacterial properties. The particles consist of polystyrene cores that are surrounded by sulfonic gel shells with embedded silver nanoparticles. The nanocomposite beads are prepared by sulfonation of polystyrene particles followed by accumulation of silver ions in the shell layer and subsequent reduction with sodium borohydride. The resulting material has been characterized by electron microscopy, vibrational and X-ray photoelectron spectroscopy and several other experimental techniques. It was shown that sodium borohydride reduces silver ions embedded in the gel layer producing silver nanoparticles but also transforms a fraction of sulfonic groups in the polymer to moieties with sulfur in a lower oxidation state, likely thiols. It is hypothesized that the generated thiol groups are anchoring the nanoparticles in the gel shell of the nanobeads stabilizing the whole structure. The silver-decorated nanobeads appear to be a promising material with considerable antimicrobial activity and were tested against Escherichia coli, Pseudomonas aeruginosa, Staphylococcus aureus and Staphylococcus epidermidis. The determined minimum inhibitory (MIC) and minimum biofilm inhibitory (MBIC) concentrations are comparable to those of non-incorporated silver nanoparticles. |
| first_indexed | 2024-12-23T11:16:32Z |
| format | Article |
| id | doaj.art-b5a06c1f44544387a3709ec02a6272da |
| institution | Directory Open Access Journal |
| issn | 2190-4286 |
| language | English |
| last_indexed | 2024-12-23T11:16:32Z |
| publishDate | 2020-04-01 |
| publisher | Beilstein-Institut |
| record_format | Article |
| series | Beilstein Journal of Nanotechnology |
| spelling | doaj.art-b5a06c1f44544387a3709ec02a6272da2022-12-21T17:49:12ZengBeilstein-InstitutBeilstein Journal of Nanotechnology2190-42862020-04-0111162063010.3762/bjnano.11.492190-4286-11-49Silver-decorated gel-shell nanobeads: physicochemical characterization and evaluation of antibacterial propertiesMarta Bartel0Katarzyna Markowska1Marcin Strawski2Krystyna Wolska3Maciej Mazur4University of Warsaw, Department of Chemistry, Pasteura 1, 02-093 Warsaw, PolandUniversity of Warsaw, Department of Biology, Miecznikowa 1, 02-093 Warsaw, PolandUniversity of Warsaw, Department of Chemistry, Pasteura 1, 02-093 Warsaw, PolandUniversity of Warsaw, Department of Biology, Miecznikowa 1, 02-093 Warsaw, PolandUniversity of Warsaw, Department of Chemistry, Pasteura 1, 02-093 Warsaw, PolandWe report on the synthesis of composite nanobeads with antibacterial properties. The particles consist of polystyrene cores that are surrounded by sulfonic gel shells with embedded silver nanoparticles. The nanocomposite beads are prepared by sulfonation of polystyrene particles followed by accumulation of silver ions in the shell layer and subsequent reduction with sodium borohydride. The resulting material has been characterized by electron microscopy, vibrational and X-ray photoelectron spectroscopy and several other experimental techniques. It was shown that sodium borohydride reduces silver ions embedded in the gel layer producing silver nanoparticles but also transforms a fraction of sulfonic groups in the polymer to moieties with sulfur in a lower oxidation state, likely thiols. It is hypothesized that the generated thiol groups are anchoring the nanoparticles in the gel shell of the nanobeads stabilizing the whole structure. The silver-decorated nanobeads appear to be a promising material with considerable antimicrobial activity and were tested against Escherichia coli, Pseudomonas aeruginosa, Staphylococcus aureus and Staphylococcus epidermidis. The determined minimum inhibitory (MIC) and minimum biofilm inhibitory (MBIC) concentrations are comparable to those of non-incorporated silver nanoparticles.https://doi.org/10.3762/bjnano.11.49escherichia coligel-shell particlesminimum biofilm inhibitory concentration (mbic)minimum inhibitory concentration (mic)nanocompositespseudomonas aeruginosasilver nanoparticlesstaphylococcus sp |
| spellingShingle | Marta Bartel Katarzyna Markowska Marcin Strawski Krystyna Wolska Maciej Mazur Silver-decorated gel-shell nanobeads: physicochemical characterization and evaluation of antibacterial properties Beilstein Journal of Nanotechnology escherichia coli gel-shell particles minimum biofilm inhibitory concentration (mbic) minimum inhibitory concentration (mic) nanocomposites pseudomonas aeruginosa silver nanoparticles staphylococcus sp |
| title | Silver-decorated gel-shell nanobeads: physicochemical characterization and evaluation of antibacterial properties |
| title_full | Silver-decorated gel-shell nanobeads: physicochemical characterization and evaluation of antibacterial properties |
| title_fullStr | Silver-decorated gel-shell nanobeads: physicochemical characterization and evaluation of antibacterial properties |
| title_full_unstemmed | Silver-decorated gel-shell nanobeads: physicochemical characterization and evaluation of antibacterial properties |
| title_short | Silver-decorated gel-shell nanobeads: physicochemical characterization and evaluation of antibacterial properties |
| title_sort | silver decorated gel shell nanobeads physicochemical characterization and evaluation of antibacterial properties |
| topic | escherichia coli gel-shell particles minimum biofilm inhibitory concentration (mbic) minimum inhibitory concentration (mic) nanocomposites pseudomonas aeruginosa silver nanoparticles staphylococcus sp |
| url | https://doi.org/10.3762/bjnano.11.49 |
| work_keys_str_mv | AT martabartel silverdecoratedgelshellnanobeadsphysicochemicalcharacterizationandevaluationofantibacterialproperties AT katarzynamarkowska silverdecoratedgelshellnanobeadsphysicochemicalcharacterizationandevaluationofantibacterialproperties AT marcinstrawski silverdecoratedgelshellnanobeadsphysicochemicalcharacterizationandevaluationofantibacterialproperties AT krystynawolska silverdecoratedgelshellnanobeadsphysicochemicalcharacterizationandevaluationofantibacterialproperties AT maciejmazur silverdecoratedgelshellnanobeadsphysicochemicalcharacterizationandevaluationofantibacterialproperties |