A Marine Alkaloid, Ascomylactam A, Suppresses Lung Tumorigenesis via Inducing Cell Cycle G1/S Arrest through ROS/Akt/Rb Pathway
Ascomylactam A was reported for the first time as a new 13-membered-ring macrocyclic alkaloid in 2019 from the mangrove endophytic fungus <i>Didymella</i> sp. CYSK-4 from the South China Sea. The aim of our study was to delineate the effects of ascomylactam A (AsA) on lung cancer cells a...
Main Authors: | Lan Wang, Yun Huang, Cui-hong Huang, Jian-chen Yu, Ying-chun Zheng, Yan Chen, Zhi-gang She, Jie Yuan |
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Format: | Article |
Language: | English |
Published: |
MDPI AG
2020-09-01
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Series: | Marine Drugs |
Subjects: | |
Online Access: | https://www.mdpi.com/1660-3397/18/10/494 |
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