Research on the fate of polymeric nanoparticles in the process of the intestinal absorption based on model nanoparticles with various characteristics: size, surface charge and pro-hydrophobics

Research on the fate of polymeric nanoparticles in the process of the intestinal absorption based on model nanoparticles with various characteristics: size, surface charge and pro-hydrophobics

Abstract Background The use of drug nanocarriers to encapsulate drugs for oral administration may become an important strategy in addressing the challenging oral absorption of some drugs. In this study—with the premise of controlling single variables—we prepared model nanoparticles with different pa...

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Bibliographic Details
Main Authors: Shiqi Guo, Yanzi Liang, Lanze Liu, Miaomiao Yin, Aiping Wang, Kaoxiang Sun, Youxin Li, Yanan Shi
Format: Article
Language:English
Published: BMC 2021-01-01
Series:Journal of Nanobiotechnology
Subjects:
Polymeric nanoparticles
Basic properties
Mucus layer
Intestinal epithelium
Physiological barrier
Online Access:https://doi.org/10.1186/s12951-021-00770-2

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