Co-administration of vaccines: a focus on tetravalent Measles-Mumps-Rubella-Varicella (MMRV) and meningococcal C conjugate vaccines

Simultaneous administration of different vaccines is a strategy to increase the possibility to receive vaccines at appropriate age, safely and effectively, reducing the number of sessions and allowing a more acceptable integration of new vaccines into National Immunization Programs (NIPs). Co-admini...

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Main Authors: Paolo Bonanni, Sara Boccalini, Angela Bechini, Ornella Varone, Giulio Matteo, Federica Sandri, Giovanni Gabutti
Format: Article
Language:English
Published: Taylor & Francis Group 2020-06-01
Series:Human Vaccines & Immunotherapeutics
Subjects:
Online Access:http://dx.doi.org/10.1080/21645515.2019.1688032
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author Paolo Bonanni
Sara Boccalini
Angela Bechini
Ornella Varone
Giulio Matteo
Federica Sandri
Giovanni Gabutti
author_facet Paolo Bonanni
Sara Boccalini
Angela Bechini
Ornella Varone
Giulio Matteo
Federica Sandri
Giovanni Gabutti
author_sort Paolo Bonanni
collection DOAJ
description Simultaneous administration of different vaccines is a strategy to increase the possibility to receive vaccines at appropriate age, safely and effectively, reducing the number of sessions and allowing a more acceptable integration of new vaccines into National Immunization Programs (NIPs). Co-administration can be performed when there are specific indications in the Summary of Product Characteristics (SmPC) of the vaccines; but, in absence of these indications, the practice is possible if there are no specific contraindications nor scientific evidence to discourage simultaneous administration. The aim of this work is to review the safety and efficacy of co-administration of the tetravalent measles, mumps, rubella, and varicella (MMRV) and the meningococcal C (Men C) conjugate vaccines after 12 months of age. Several studies demonstrated that MMRV and Men C conjugate vaccines can be administered concomitantly without a negative impact on the safety and immunogenicity of either vaccines, inducing highly immunogenic responses.
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spelling doaj.art-b5aa70879ec84933a5de504c8c6e97a92023-09-22T08:45:34ZengTaylor & Francis GroupHuman Vaccines & Immunotherapeutics2164-55152164-554X2020-06-011661313132110.1080/21645515.2019.16880321688032Co-administration of vaccines: a focus on tetravalent Measles-Mumps-Rubella-Varicella (MMRV) and meningococcal C conjugate vaccinesPaolo Bonanni0Sara Boccalini1Angela Bechini2Ornella Varone3Giulio Matteo4Federica Sandri5Giovanni Gabutti6University of FlorenceUniversity of FlorenceUniversity of FlorenceUniversity of FlorenceUniversity of FerraraUniversity of FerraraUniversity of FerraraSimultaneous administration of different vaccines is a strategy to increase the possibility to receive vaccines at appropriate age, safely and effectively, reducing the number of sessions and allowing a more acceptable integration of new vaccines into National Immunization Programs (NIPs). Co-administration can be performed when there are specific indications in the Summary of Product Characteristics (SmPC) of the vaccines; but, in absence of these indications, the practice is possible if there are no specific contraindications nor scientific evidence to discourage simultaneous administration. The aim of this work is to review the safety and efficacy of co-administration of the tetravalent measles, mumps, rubella, and varicella (MMRV) and the meningococcal C (Men C) conjugate vaccines after 12 months of age. Several studies demonstrated that MMRV and Men C conjugate vaccines can be administered concomitantly without a negative impact on the safety and immunogenicity of either vaccines, inducing highly immunogenic responses.http://dx.doi.org/10.1080/21645515.2019.1688032co-administrationsafetyefficacymeningococcal c vaccinemeaslesmumpsrubellavaricella vaccine
spellingShingle Paolo Bonanni
Sara Boccalini
Angela Bechini
Ornella Varone
Giulio Matteo
Federica Sandri
Giovanni Gabutti
Co-administration of vaccines: a focus on tetravalent Measles-Mumps-Rubella-Varicella (MMRV) and meningococcal C conjugate vaccines
Human Vaccines & Immunotherapeutics
co-administration
safety
efficacy
meningococcal c vaccine
measles
mumps
rubella
varicella vaccine
title Co-administration of vaccines: a focus on tetravalent Measles-Mumps-Rubella-Varicella (MMRV) and meningococcal C conjugate vaccines
title_full Co-administration of vaccines: a focus on tetravalent Measles-Mumps-Rubella-Varicella (MMRV) and meningococcal C conjugate vaccines
title_fullStr Co-administration of vaccines: a focus on tetravalent Measles-Mumps-Rubella-Varicella (MMRV) and meningococcal C conjugate vaccines
title_full_unstemmed Co-administration of vaccines: a focus on tetravalent Measles-Mumps-Rubella-Varicella (MMRV) and meningococcal C conjugate vaccines
title_short Co-administration of vaccines: a focus on tetravalent Measles-Mumps-Rubella-Varicella (MMRV) and meningococcal C conjugate vaccines
title_sort co administration of vaccines a focus on tetravalent measles mumps rubella varicella mmrv and meningococcal c conjugate vaccines
topic co-administration
safety
efficacy
meningococcal c vaccine
measles
mumps
rubella
varicella vaccine
url http://dx.doi.org/10.1080/21645515.2019.1688032
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