Research progress in degradation behavior of biodegradable medical Mg-based alloys <i>in vivo</i> and <i>in vitro</i>
As a new generation of medical degradable biomaterials, magnesium alloys were known as "revolutionary medical metal materials" due to their good biocompatibility, unique degradability and excellent mechanical transmission. However, the corrosion resistance of magnesium alloys is poor and t...
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| Format: | Article |
| Language: | zho |
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Journal of Materials Engineering
2021-05-01
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| Series: | Cailiao gongcheng |
| Subjects: | |
| Online Access: | http://jme.biam.ac.cn/CN/10.11868/j.issn.1001-4381.2020.000338 |
| _version_ | 1797968719363702784 |
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| author | TIAN Ya-qiang ZHAO Guan-zhang LIU Yun ZHANG Yuan ZHENG Xiao-ping CHEN Lian-sheng |
| author_facet | TIAN Ya-qiang ZHAO Guan-zhang LIU Yun ZHANG Yuan ZHENG Xiao-ping CHEN Lian-sheng |
| author_sort | TIAN Ya-qiang |
| collection | DOAJ |
| description | As a new generation of medical degradable biomaterials, magnesium alloys were known as "revolutionary medical metal materials" due to their good biocompatibility, unique degradability and excellent mechanical transmission. However, the corrosion resistance of magnesium alloys is poor and there are phenomena such as rapid and uneven degradation.The research progress in improving the degradation properties of magnesium alloys was introduced from four aspects: microalloying, heat treatment process, plastic deformation and surface modification. The degradation rate and degradation modes of medical magnesium alloys <i>in vivo</i> and <i>in vitro</i> under different processing methods were compared. The influence of microstructure evolution and film characteristics of magnesium alloys under different processing conditions on the destruction mechanism of the Cl<sup>-</sup> for the film layer and the three-dimensional degradation morphology were revealed.The correlation data analysis model between different process conditions and corrosion degradation rate of magnesium alloys in simulated solution was established.Finally, it was pointed out that the focus of future research in this field is to analyse the main action mechanism of microstructure on magnesium alloys degradation properties from multiple perspectives and to build a prediction model of microstructure on magnesium alloys degradation life. |
| first_indexed | 2024-04-11T02:51:13Z |
| format | Article |
| id | doaj.art-b5b4c8f126aa41178f928ac690203c32 |
| institution | Directory Open Access Journal |
| issn | 1001-4381 1001-4381 |
| language | zho |
| last_indexed | 2024-04-11T02:51:13Z |
| publishDate | 2021-05-01 |
| publisher | Journal of Materials Engineering |
| record_format | Article |
| series | Cailiao gongcheng |
| spelling | doaj.art-b5b4c8f126aa41178f928ac690203c322023-01-02T16:33:53ZzhoJournal of Materials EngineeringCailiao gongcheng1001-43811001-43812021-05-01495243710.11868/j.issn.1001-4381.2020.00033820210502Research progress in degradation behavior of biodegradable medical Mg-based alloys <i>in vivo</i> and <i>in vitro</i>TIAN Ya-qiang0ZHAO Guan-zhang1LIU Yun2ZHANG Yuan3ZHENG Xiao-ping4CHEN Lian-sheng5Key Laboratory of the Ministry of Education for Modern Metallurgy Technology, North China University of Science and Technology, Tangshan 063210, Hebei, ChinaKey Laboratory of the Ministry of Education for Modern Metallurgy Technology, North China University of Science and Technology, Tangshan 063210, Hebei, ChinaKey Laboratory of the Ministry of Education for Modern Metallurgy Technology, North China University of Science and Technology, Tangshan 063210, Hebei, ChinaKey Laboratory of the Ministry of Education for Modern Metallurgy Technology, North China University of Science and Technology, Tangshan 063210, Hebei, ChinaKey Laboratory of the Ministry of Education for Modern Metallurgy Technology, North China University of Science and Technology, Tangshan 063210, Hebei, ChinaKey Laboratory of the Ministry of Education for Modern Metallurgy Technology, North China University of Science and Technology, Tangshan 063210, Hebei, ChinaAs a new generation of medical degradable biomaterials, magnesium alloys were known as "revolutionary medical metal materials" due to their good biocompatibility, unique degradability and excellent mechanical transmission. However, the corrosion resistance of magnesium alloys is poor and there are phenomena such as rapid and uneven degradation.The research progress in improving the degradation properties of magnesium alloys was introduced from four aspects: microalloying, heat treatment process, plastic deformation and surface modification. The degradation rate and degradation modes of medical magnesium alloys <i>in vivo</i> and <i>in vitro</i> under different processing methods were compared. The influence of microstructure evolution and film characteristics of magnesium alloys under different processing conditions on the destruction mechanism of the Cl<sup>-</sup> for the film layer and the three-dimensional degradation morphology were revealed.The correlation data analysis model between different process conditions and corrosion degradation rate of magnesium alloys in simulated solution was established.Finally, it was pointed out that the focus of future research in this field is to analyse the main action mechanism of microstructure on magnesium alloys degradation properties from multiple perspectives and to build a prediction model of microstructure on magnesium alloys degradation life.http://jme.biam.ac.cn/CN/10.11868/j.issn.1001-4381.2020.000338degradable mg alloydegradation <i>in vivo</i>degradation <i>in vitro</i>degradation ratefilm layer feature |
| spellingShingle | TIAN Ya-qiang ZHAO Guan-zhang LIU Yun ZHANG Yuan ZHENG Xiao-ping CHEN Lian-sheng Research progress in degradation behavior of biodegradable medical Mg-based alloys <i>in vivo</i> and <i>in vitro</i> Cailiao gongcheng degradable mg alloy degradation <i>in vivo</i> degradation <i>in vitro</i> degradation rate film layer feature |
| title | Research progress in degradation behavior of biodegradable medical Mg-based alloys <i>in vivo</i> and <i>in vitro</i> |
| title_full | Research progress in degradation behavior of biodegradable medical Mg-based alloys <i>in vivo</i> and <i>in vitro</i> |
| title_fullStr | Research progress in degradation behavior of biodegradable medical Mg-based alloys <i>in vivo</i> and <i>in vitro</i> |
| title_full_unstemmed | Research progress in degradation behavior of biodegradable medical Mg-based alloys <i>in vivo</i> and <i>in vitro</i> |
| title_short | Research progress in degradation behavior of biodegradable medical Mg-based alloys <i>in vivo</i> and <i>in vitro</i> |
| title_sort | research progress in degradation behavior of biodegradable medical mg based alloys i in vivo i and i in vitro i |
| topic | degradable mg alloy degradation <i>in vivo</i> degradation <i>in vitro</i> degradation rate film layer feature |
| url | http://jme.biam.ac.cn/CN/10.11868/j.issn.1001-4381.2020.000338 |
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