Allelic and genotype frequencies of major CYP2B6 polymorphisms in the Pakistani population

Allelic and genotype frequencies of major CYP2B6 polymorphisms in the Pakistani population

Abstract Background Cytochrome P450 (CYP2B6) is an important enzyme that metabolizes about 3.0% of therapeutic drugs. Drugs metabolized mainly by CYP2B6 include artemisinin, bupropion, cyclophosphamide, efavirenz, ketamine, and methadone. The genetic polymorphisms in the CYP2B6 gene have earlier bee...

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Bibliographic Details
Main Authors: Sagheer Ahmed, Saeed Khan, Kholood Janjua, Imran Imran, Arif Ullah Khan
Format: Article
Language:English
Published: Wiley 2021-03-01
Series:Molecular Genetics & Genomic Medicine
Subjects:
CYP2B6
Pakistani population
pharmacogenetics
polymorphisms
Online Access:https://doi.org/10.1002/mgg3.1527

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