In vitro study on the preventive effect of children’s toothpastes on erosive tooth wear of primary bovine enamel and dentin
Abstract This in vitro study aimed to analyse the effect of various children’s toothpastes on erosive tooth wear of primary bovine enamel and dentin. Enamel and dentin specimens (n = 12) were cyclically eroded (6 × 60 s/d, citric acid, pH 2.4) and brushed (2 × 15 s/d, 2 N) over 5 days. Nine fluoride...
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| Format: | Article |
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Nature Portfolio
2023-07-01
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| Series: | Scientific Reports |
| Online Access: | https://doi.org/10.1038/s41598-023-38043-7 |
| _version_ | 1797784717664190464 |
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| author | Jennifer Chalkidis Sarah Barke Bianca Rohland Alexandra Schmidt Philipp Kanzow Annette Wiegand |
| author_facet | Jennifer Chalkidis Sarah Barke Bianca Rohland Alexandra Schmidt Philipp Kanzow Annette Wiegand |
| author_sort | Jennifer Chalkidis |
| collection | DOAJ |
| description | Abstract This in vitro study aimed to analyse the effect of various children’s toothpastes on erosive tooth wear of primary bovine enamel and dentin. Enamel and dentin specimens (n = 12) were cyclically eroded (6 × 60 s/d, citric acid, pH 2.4) and brushed (2 × 15 s/d, 2 N) over 5 days. Nine fluoride toothpastes (500 to 1450 ppm) and eight toothpastes containing no fluoride or other active ingredients (hydroxyapatite and/or xylitol) were tested. Unbrushed specimens served as control. Tissue loss was quantified using widefield confocal microscopy and statistically analysed using two-way and one-way ANOVAs followed by Scheffe’s (enamel) or Tamhane’s (dentin) post-hoc tests (p < 0.05). Only one fluoride toothpaste (1400 ppm) was able to reduce erosive wear of enamel significantly by 15% compared to the control (padj. = 0.002). All fluoridated toothpastes reduced dentin surface loss significantly by 32 to 69% compared to the control (padj. ≤ 0.001), while fluoride-free toothpastes were unable to reduce dentin loss significantly (padj. ≥ 0.971). Most fluoridated toothpastes caused less erosive wear compared to fluoride-free toothpastes. Children toothpastes containing fluoride were more effective in reducing erosive wear compared to toothpastes containing no fluoride or other active ingredients. |
| first_indexed | 2024-03-13T00:43:52Z |
| format | Article |
| id | doaj.art-b5bba973933f4c739acd6b6d50216d51 |
| institution | Directory Open Access Journal |
| issn | 2045-2322 |
| language | English |
| last_indexed | 2024-03-13T00:43:52Z |
| publishDate | 2023-07-01 |
| publisher | Nature Portfolio |
| record_format | Article |
| series | Scientific Reports |
| spelling | doaj.art-b5bba973933f4c739acd6b6d50216d512023-07-09T11:10:42ZengNature PortfolioScientific Reports2045-23222023-07-011311810.1038/s41598-023-38043-7In vitro study on the preventive effect of children’s toothpastes on erosive tooth wear of primary bovine enamel and dentinJennifer Chalkidis0Sarah Barke1Bianca Rohland2Alexandra Schmidt3Philipp Kanzow4Annette Wiegand5Department of Preventive Dentistry, Periodontology and Cariology, University Medical Center GöttingenDepartment of Preventive Dentistry, Periodontology and Cariology, University Medical Center GöttingenDepartment of Preventive Dentistry, Periodontology and Cariology, University Medical Center GöttingenDepartment of Preventive Dentistry, Periodontology and Cariology, University Medical Center GöttingenDepartment of Preventive Dentistry, Periodontology and Cariology, University Medical Center GöttingenDepartment of Preventive Dentistry, Periodontology and Cariology, University Medical Center GöttingenAbstract This in vitro study aimed to analyse the effect of various children’s toothpastes on erosive tooth wear of primary bovine enamel and dentin. Enamel and dentin specimens (n = 12) were cyclically eroded (6 × 60 s/d, citric acid, pH 2.4) and brushed (2 × 15 s/d, 2 N) over 5 days. Nine fluoride toothpastes (500 to 1450 ppm) and eight toothpastes containing no fluoride or other active ingredients (hydroxyapatite and/or xylitol) were tested. Unbrushed specimens served as control. Tissue loss was quantified using widefield confocal microscopy and statistically analysed using two-way and one-way ANOVAs followed by Scheffe’s (enamel) or Tamhane’s (dentin) post-hoc tests (p < 0.05). Only one fluoride toothpaste (1400 ppm) was able to reduce erosive wear of enamel significantly by 15% compared to the control (padj. = 0.002). All fluoridated toothpastes reduced dentin surface loss significantly by 32 to 69% compared to the control (padj. ≤ 0.001), while fluoride-free toothpastes were unable to reduce dentin loss significantly (padj. ≥ 0.971). Most fluoridated toothpastes caused less erosive wear compared to fluoride-free toothpastes. Children toothpastes containing fluoride were more effective in reducing erosive wear compared to toothpastes containing no fluoride or other active ingredients.https://doi.org/10.1038/s41598-023-38043-7 |
| spellingShingle | Jennifer Chalkidis Sarah Barke Bianca Rohland Alexandra Schmidt Philipp Kanzow Annette Wiegand In vitro study on the preventive effect of children’s toothpastes on erosive tooth wear of primary bovine enamel and dentin Scientific Reports |
| title | In vitro study on the preventive effect of children’s toothpastes on erosive tooth wear of primary bovine enamel and dentin |
| title_full | In vitro study on the preventive effect of children’s toothpastes on erosive tooth wear of primary bovine enamel and dentin |
| title_fullStr | In vitro study on the preventive effect of children’s toothpastes on erosive tooth wear of primary bovine enamel and dentin |
| title_full_unstemmed | In vitro study on the preventive effect of children’s toothpastes on erosive tooth wear of primary bovine enamel and dentin |
| title_short | In vitro study on the preventive effect of children’s toothpastes on erosive tooth wear of primary bovine enamel and dentin |
| title_sort | in vitro study on the preventive effect of children s toothpastes on erosive tooth wear of primary bovine enamel and dentin |
| url | https://doi.org/10.1038/s41598-023-38043-7 |
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