Opioid-free versus Opioid-Based General Anesthesia in Cesarean Sections: A Cross-sectional Analysis
Aim:Guidelines recommend opioid-free (OF) anesthesia in elective cesarean sections (CS). However, opioids are commonly administered after a baby’s delivery for postoperative pain in daily practice. Our aim was to compare OF and opioid-based (OB) general anesthesia in elective surgery (CS).Methods:Th...
| Main Authors: | , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Galenos Yayinevi
2023-06-01
|
| Series: | Haseki Tıp Bülteni |
| Subjects: | |
| Online Access: |
http://www.hasekidergisi.com/archives/archive-detail/article-preview/opioid-free-versus-opioid-based-general-anesthesia/60792
|
| _version_ | 1797787145833807872 |
|---|---|
| author | Elif Ongel Burcu Saglanmak Esra Adiyeke Nurten Bakan |
| author_facet | Elif Ongel Burcu Saglanmak Esra Adiyeke Nurten Bakan |
| author_sort | Elif Ongel |
| collection | DOAJ |
| description | Aim:Guidelines recommend opioid-free (OF) anesthesia in elective cesarean sections (CS). However, opioids are commonly administered after a baby’s delivery for postoperative pain in daily practice. Our aim was to compare OF and opioid-based (OB) general anesthesia in elective surgery (CS).Methods:The study was a cross-sectional study including patients who had undergone elective CS with OF (Group OF) and OB (Group OB) general anesthesia between June 1, 2022, and November 30, 2022. Intraoperatively administered analgesics for postoperative pain mainly included acetaminophen and non-steroidal anti-inflammatory drugs (NSAID) in Group OF and fentanyl, acetaminophen, and tramadol in Group OB. Non-steroidal anti-inflammatory drugs were administered as analgesics at the maternity ward.Results:Of 368 patients, 278 were excluded due to regional anesthesia. In 90 patients, 45 were in Group OF and 45 were in Group OB. Group OF received less intraoperative fluid compared with Group OB. Two groups required a similar number of NSAIDs on postoperative day zero. Group OF had more NSAID consumption on postoperative days one and two.Conclusion:Opioid-free general anesthesia did not change the required number of NSAIDs 24 hours after surgery and necessitated less intraoperative crystalloid fluid. Our study supports Enhanced recovery after surgery protocols, which recommend multimodal analgesics and sparing opioids in CS, and adds to the accumulating evidence that suggests the use of OF general anesthesia in CS. |
| first_indexed | 2024-03-13T01:17:49Z |
| format | Article |
| id | doaj.art-b5bce70887854f059f3076474a43cfd7 |
| institution | Directory Open Access Journal |
| issn | 1302-0072 2147-2688 |
| language | English |
| last_indexed | 2024-03-13T01:17:49Z |
| publishDate | 2023-06-01 |
| publisher | Galenos Yayinevi |
| record_format | Article |
| series | Haseki Tıp Bülteni |
| spelling | doaj.art-b5bce70887854f059f3076474a43cfd72023-07-05T08:52:23ZengGalenos YayineviHaseki Tıp Bülteni1302-00722147-26882023-06-0161317217710.4274/haseki.galenos.2023.909013049054Opioid-free versus Opioid-Based General Anesthesia in Cesarean Sections: A Cross-sectional AnalysisElif Ongel0Burcu Saglanmak1Esra Adiyeke2Nurten Bakan3 University of Health Sciences Turkey, Istanbul Sancaktepe Sehit Prof. Dr. Ilhan Varank Training and Research Hospital, Clinic of Anesthesiology and Reanimation, Istanbul, Turkey University of Health Sciences Turkey, Istanbul Sancaktepe Sehit Prof. Dr. Ilhan Varank Training and Research Hospital, Clinic of Anesthesiology and Reanimation, Istanbul, Turkey University of Health Sciences Turkey, Istanbul Sancaktepe Sehit Prof. Dr. Ilhan Varank Training and Research Hospital, Clinic of Anesthesiology and Reanimation, Istanbul, Turkey University of Health Sciences Turkey, Istanbul Sancaktepe Sehit Prof. Dr. Ilhan Varank Training and Research Hospital, Clinic of Anesthesiology and Reanimation, Istanbul, Turkey Aim:Guidelines recommend opioid-free (OF) anesthesia in elective cesarean sections (CS). However, opioids are commonly administered after a baby’s delivery for postoperative pain in daily practice. Our aim was to compare OF and opioid-based (OB) general anesthesia in elective surgery (CS).Methods:The study was a cross-sectional study including patients who had undergone elective CS with OF (Group OF) and OB (Group OB) general anesthesia between June 1, 2022, and November 30, 2022. Intraoperatively administered analgesics for postoperative pain mainly included acetaminophen and non-steroidal anti-inflammatory drugs (NSAID) in Group OF and fentanyl, acetaminophen, and tramadol in Group OB. Non-steroidal anti-inflammatory drugs were administered as analgesics at the maternity ward.Results:Of 368 patients, 278 were excluded due to regional anesthesia. In 90 patients, 45 were in Group OF and 45 were in Group OB. Group OF received less intraoperative fluid compared with Group OB. Two groups required a similar number of NSAIDs on postoperative day zero. Group OF had more NSAID consumption on postoperative days one and two.Conclusion:Opioid-free general anesthesia did not change the required number of NSAIDs 24 hours after surgery and necessitated less intraoperative crystalloid fluid. Our study supports Enhanced recovery after surgery protocols, which recommend multimodal analgesics and sparing opioids in CS, and adds to the accumulating evidence that suggests the use of OF general anesthesia in CS. http://www.hasekidergisi.com/archives/archive-detail/article-preview/opioid-free-versus-opioid-based-general-anesthesia/60792 obstetricscesarean sectiongeneral anesthesiaopioid analgesicspostoperative painperioperative care |
| spellingShingle | Elif Ongel Burcu Saglanmak Esra Adiyeke Nurten Bakan Opioid-free versus Opioid-Based General Anesthesia in Cesarean Sections: A Cross-sectional Analysis Haseki Tıp Bülteni obstetrics cesarean section general anesthesia opioid analgesics postoperative pain perioperative care |
| title | Opioid-free versus Opioid-Based General Anesthesia in Cesarean Sections: A Cross-sectional Analysis |
| title_full | Opioid-free versus Opioid-Based General Anesthesia in Cesarean Sections: A Cross-sectional Analysis |
| title_fullStr | Opioid-free versus Opioid-Based General Anesthesia in Cesarean Sections: A Cross-sectional Analysis |
| title_full_unstemmed | Opioid-free versus Opioid-Based General Anesthesia in Cesarean Sections: A Cross-sectional Analysis |
| title_short | Opioid-free versus Opioid-Based General Anesthesia in Cesarean Sections: A Cross-sectional Analysis |
| title_sort | opioid free versus opioid based general anesthesia in cesarean sections a cross sectional analysis |
| topic | obstetrics cesarean section general anesthesia opioid analgesics postoperative pain perioperative care |
| url |
http://www.hasekidergisi.com/archives/archive-detail/article-preview/opioid-free-versus-opioid-based-general-anesthesia/60792
|
| work_keys_str_mv | AT elifongel opioidfreeversusopioidbasedgeneralanesthesiaincesareansectionsacrosssectionalanalysis AT burcusaglanmak opioidfreeversusopioidbasedgeneralanesthesiaincesareansectionsacrosssectionalanalysis AT esraadiyeke opioidfreeversusopioidbasedgeneralanesthesiaincesareansectionsacrosssectionalanalysis AT nurtenbakan opioidfreeversusopioidbasedgeneralanesthesiaincesareansectionsacrosssectionalanalysis |