Adult Mesenchymal Stem Cells for Tissue Engineering

The identification of multipotential mesenchymal stem cells (MSCs) derived from adult human tissues such as bone marrow and connective tissues has provided exciting prospects for cell-based tissue engineering and regeneration. This review article focuses on the biology of MSCs, their differentiation...

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Main Authors: Reza Samanipour, Batool Hashemibeni, Elahe Pourazizi Najafabadi
Format: Article
Language:English
Published: Negah Institute for Scientific Communication 2016-01-01
Series:Anatomical Sciences Journal
Subjects:
Online Access:http://anatomyjournal.ir/article-1-127-en.html
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author Reza Samanipour
Batool Hashemibeni
Elahe Pourazizi Najafabadi
author_facet Reza Samanipour
Batool Hashemibeni
Elahe Pourazizi Najafabadi
author_sort Reza Samanipour
collection DOAJ
description The identification of multipotential mesenchymal stem cells (MSCs) derived from adult human tissues such as bone marrow and connective tissues has provided exciting prospects for cell-based tissue engineering and regeneration. This review article focuses on the biology of MSCs, their differentiation potentials in vitro and in vivo, and their application in tissue engineering. Our current understanding of MSCs lags behind that of other stem cell types, such as hematopoietic stem cells. Future research should aim to define the cellular and molecular fingerprints of MSCs and elucidate their endogenous role(s) in normal and abnormal tissue functions.
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spelling doaj.art-b5bda233368240b3956f973c21dbb0622022-12-21T20:15:42ZengNegah Institute for Scientific CommunicationAnatomical Sciences Journal2322-36262322-36262016-01-011311318Adult Mesenchymal Stem Cells for Tissue EngineeringReza Samanipour0Batool Hashemibeni1Elahe Pourazizi Najafabadi2 Department of Nuclear Engineering, Faculty of Nuclear Engineering and Basic Sciences, Najafabad Branch, Islamic Azad University, Najafabad, Iran. Department of Anatomical Sciences, School of Medicine, Isfahan University of Medical Sciences, Isfahan, Iran. Department of Nuclear Engineering, Faculty of Nuclear Engineering and Basic Sciences, Najafabad Branch, Islamic Azad University, Najafabad, Iran. The identification of multipotential mesenchymal stem cells (MSCs) derived from adult human tissues such as bone marrow and connective tissues has provided exciting prospects for cell-based tissue engineering and regeneration. This review article focuses on the biology of MSCs, their differentiation potentials in vitro and in vivo, and their application in tissue engineering. Our current understanding of MSCs lags behind that of other stem cell types, such as hematopoietic stem cells. Future research should aim to define the cellular and molecular fingerprints of MSCs and elucidate their endogenous role(s) in normal and abnormal tissue functions.http://anatomyjournal.ir/article-1-127-en.htmlmultipotential mesenchymal stem cells (mscs)tissue engineeringregenerationdifferentiation
spellingShingle Reza Samanipour
Batool Hashemibeni
Elahe Pourazizi Najafabadi
Adult Mesenchymal Stem Cells for Tissue Engineering
Anatomical Sciences Journal
multipotential mesenchymal stem cells (mscs)
tissue engineering
regeneration
differentiation
title Adult Mesenchymal Stem Cells for Tissue Engineering
title_full Adult Mesenchymal Stem Cells for Tissue Engineering
title_fullStr Adult Mesenchymal Stem Cells for Tissue Engineering
title_full_unstemmed Adult Mesenchymal Stem Cells for Tissue Engineering
title_short Adult Mesenchymal Stem Cells for Tissue Engineering
title_sort adult mesenchymal stem cells for tissue engineering
topic multipotential mesenchymal stem cells (mscs)
tissue engineering
regeneration
differentiation
url http://anatomyjournal.ir/article-1-127-en.html
work_keys_str_mv AT rezasamanipour adultmesenchymalstemcellsfortissueengineering
AT batoolhashemibeni adultmesenchymalstemcellsfortissueengineering
AT elahepourazizinajafabadi adultmesenchymalstemcellsfortissueengineering