Scientific Opinion on Flavouring Group Evaluation 401 (FGE.401): γ-Glutamyl-valyl-glycine from chemical group 34

The Panel on Food Contact Materials, Enzymes, Flavourings and Processing Aids of the European Food Safety Authority was requested to carry out a safety assessment of one flavouring substance, γ-glutamyl-valyl-glycine [FL-no: 17.038], in the Flavouring Group Evaluation 401 (FGE.401), in accordance wi...

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Main Author: EFSA Panel on Food Contact Materials, Enzymes, Flavourings and Processing Aids (CEF)
Format: Article
Language:English
Published: Wiley 2014-04-01
Series:EFSA Journal
Subjects:
Online Access:http://www.efsa.europa.eu/en/efsajournal/doc/3625.pdf
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author EFSA Panel on Food Contact Materials, Enzymes, Flavourings and Processing Aids (CEF)
author_facet EFSA Panel on Food Contact Materials, Enzymes, Flavourings and Processing Aids (CEF)
author_sort EFSA Panel on Food Contact Materials, Enzymes, Flavourings and Processing Aids (CEF)
collection DOAJ
description The Panel on Food Contact Materials, Enzymes, Flavourings and Processing Aids of the European Food Safety Authority was requested to carry out a safety assessment of one flavouring substance, γ-glutamyl-valyl-glycine [FL-no: 17.038], in the Flavouring Group Evaluation 401 (FGE.401), in accordance with the Commission Regulation (EC) No 1331/2008. There is no safety concern with respect to genotoxicity for the flavouring substance. It has been demonstrated that the flavouring substance, which is a tripeptide, will be hydrolysed to the three amino acids L-glutamic acid, L-valine and glycine. As the human consumption of these three endogenous amino acids through food is orders of magnitude higher than the anticipated levels of exposure from their use as flavouring substances, the Panel concluded that γ-glutamyl-valyl-glycine [FL-no: 17.038] would be of no safety concern at its estimated level of intake as flavouring substance. The specifications for γ-glutamyl-valyl-glycine [FL-no: 17.038] are considered adequate according to Commission Regulation (EC) no 1334/2008.
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spelling doaj.art-b5bdceb170074cf29a9ddbda369998da2022-12-21T22:30:14ZengWileyEFSA Journal1831-47322014-04-0112410.2903/j.efsa.2014.3625EFSA Journal 2014;12(4):3625Scientific Opinion on Flavouring Group Evaluation 401 (FGE.401): γ-Glutamyl-valyl-glycine from chemical group 34EFSA Panel on Food Contact Materials, Enzymes, Flavourings and Processing Aids (CEF)The Panel on Food Contact Materials, Enzymes, Flavourings and Processing Aids of the European Food Safety Authority was requested to carry out a safety assessment of one flavouring substance, γ-glutamyl-valyl-glycine [FL-no: 17.038], in the Flavouring Group Evaluation 401 (FGE.401), in accordance with the Commission Regulation (EC) No 1331/2008. There is no safety concern with respect to genotoxicity for the flavouring substance. It has been demonstrated that the flavouring substance, which is a tripeptide, will be hydrolysed to the three amino acids L-glutamic acid, L-valine and glycine. As the human consumption of these three endogenous amino acids through food is orders of magnitude higher than the anticipated levels of exposure from their use as flavouring substances, the Panel concluded that γ-glutamyl-valyl-glycine [FL-no: 17.038] would be of no safety concern at its estimated level of intake as flavouring substance. The specifications for γ-glutamyl-valyl-glycine [FL-no: 17.038] are considered adequate according to Commission Regulation (EC) no 1334/2008.http://www.efsa.europa.eu/en/efsajournal/doc/3625.pdffood safetyflavouring?-glutamyl-valyl-glycine[FL-no: 17.038]CASrn 38837-70-6
spellingShingle EFSA Panel on Food Contact Materials, Enzymes, Flavourings and Processing Aids (CEF)
Scientific Opinion on Flavouring Group Evaluation 401 (FGE.401): γ-Glutamyl-valyl-glycine from chemical group 34
EFSA Journal
food safety
flavouring
?-glutamyl-valyl-glycine
[FL-no: 17.038]
CASrn 38837-70-6
title Scientific Opinion on Flavouring Group Evaluation 401 (FGE.401): γ-Glutamyl-valyl-glycine from chemical group 34
title_full Scientific Opinion on Flavouring Group Evaluation 401 (FGE.401): γ-Glutamyl-valyl-glycine from chemical group 34
title_fullStr Scientific Opinion on Flavouring Group Evaluation 401 (FGE.401): γ-Glutamyl-valyl-glycine from chemical group 34
title_full_unstemmed Scientific Opinion on Flavouring Group Evaluation 401 (FGE.401): γ-Glutamyl-valyl-glycine from chemical group 34
title_short Scientific Opinion on Flavouring Group Evaluation 401 (FGE.401): γ-Glutamyl-valyl-glycine from chemical group 34
title_sort scientific opinion on flavouring group evaluation 401 fge 401 γ glutamyl valyl glycine from chemical group 34
topic food safety
flavouring
?-glutamyl-valyl-glycine
[FL-no: 17.038]
CASrn 38837-70-6
url http://www.efsa.europa.eu/en/efsajournal/doc/3625.pdf
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