Retroviral Disease and Smoking – A Sinister Combination causing Hyperkeratotic Laryngeal Papilloma

Introduction Otorhinolaryngologic manifestations account for almost 80% of the various manifestations of Human Immunodeficiency Virus (HIV) infection, of which Human Papilloma Virus (HPV) associated laryngeal papilloma and laryngeal malignancy are the most common pertaining to larynx. Case Repo...

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Main Authors: Bharathi M B, Rakesh B S, Thanzeem Unisa, Kavya S
Format: Article
Language:English
Published: The Association of Otolaryngologists of India, West Bengal 2022-03-01
Series:Bengal Journal of Otolaryngology and Head Neck Surgery
Subjects:
Online Access:https://www.bjohns.in/journal3/index.php/bjohns/article/view/570
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author Bharathi M B
Rakesh B S
Thanzeem Unisa
Kavya S
author_facet Bharathi M B
Rakesh B S
Thanzeem Unisa
Kavya S
author_sort Bharathi M B
collection DOAJ
description Introduction Otorhinolaryngologic manifestations account for almost 80% of the various manifestations of Human Immunodeficiency Virus (HIV) infection, of which Human Papilloma Virus (HPV) associated laryngeal papilloma and laryngeal malignancy are the most common pertaining to larynx. Case Report A 55year old male patient on Antiretroviral treatment since 10 years who was a chronic smoker, presented with difficulty in breathing and hoarseness of voice. Flexible laryngoscopy revealed a white, horny, wide based keratotic lesion completely covering rima glottidis resulting in obstruction of airway and stridor. Tracheostomy was done followed by        endoscopic excision of the lesion. Histopathologic examination showed features of hyperkeratotic papilloma and lesion was tested negative for HPV. Discussion We report this case to emphasize on the differential diagnosis of laryngeal papillomatous lesion. A hyperkeratotic papilloma, with a dual aetiology of retroviral disease  and smoking, presenting with stridor, the lesion being negative for HPV infection makes it uncommon from other laryngeal lesions.
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spelling doaj.art-b5c09826622c4779856397789b408f452024-03-03T00:51:49ZengThe Association of Otolaryngologists of India, West BengalBengal Journal of Otolaryngology and Head Neck Surgery2395-24072022-03-0129310.47210/bjohns.2021.v29i3.570Retroviral Disease and Smoking – A Sinister Combination causing Hyperkeratotic Laryngeal PapillomaBharathi M B0Rakesh B S1Thanzeem Unisa2Kavya S3Professor, Department of ENT,Head and Neck Surgery, JSS Medical College and Hospital, JSS Academy of Higher Education and Research, Mysuru, Karnataka - 570004, IndiaAssistant Professor, Department of ENT,Head and Neck Surgery,JSS Medical College and Hospital, JSS Academy of Higher Education and Research, Mysuru, Karnataka - 570004, IndiaSenior Resident, Department of ENT,Head and Neck Surgery, JSS Medical College and Hospital, JSS Academy of Higher Education and Research, Mysuru, Karnataka - 570004, IndiaJunior Resident, Department of ENT,Head and Neck Surgery,JSS Medical College and Hospital, JSS Academy of Higher Education and Research, Mysuru, Karnataka - 570004, India Introduction Otorhinolaryngologic manifestations account for almost 80% of the various manifestations of Human Immunodeficiency Virus (HIV) infection, of which Human Papilloma Virus (HPV) associated laryngeal papilloma and laryngeal malignancy are the most common pertaining to larynx. Case Report A 55year old male patient on Antiretroviral treatment since 10 years who was a chronic smoker, presented with difficulty in breathing and hoarseness of voice. Flexible laryngoscopy revealed a white, horny, wide based keratotic lesion completely covering rima glottidis resulting in obstruction of airway and stridor. Tracheostomy was done followed by        endoscopic excision of the lesion. Histopathologic examination showed features of hyperkeratotic papilloma and lesion was tested negative for HPV. Discussion We report this case to emphasize on the differential diagnosis of laryngeal papillomatous lesion. A hyperkeratotic papilloma, with a dual aetiology of retroviral disease  and smoking, presenting with stridor, the lesion being negative for HPV infection makes it uncommon from other laryngeal lesions. https://www.bjohns.in/journal3/index.php/bjohns/article/view/570Papilloma, HyperkeratoticLarynxHIVSmoking
spellingShingle Bharathi M B
Rakesh B S
Thanzeem Unisa
Kavya S
Retroviral Disease and Smoking – A Sinister Combination causing Hyperkeratotic Laryngeal Papilloma
Bengal Journal of Otolaryngology and Head Neck Surgery
Papilloma, Hyperkeratotic
Larynx
HIV
Smoking
title Retroviral Disease and Smoking – A Sinister Combination causing Hyperkeratotic Laryngeal Papilloma
title_full Retroviral Disease and Smoking – A Sinister Combination causing Hyperkeratotic Laryngeal Papilloma
title_fullStr Retroviral Disease and Smoking – A Sinister Combination causing Hyperkeratotic Laryngeal Papilloma
title_full_unstemmed Retroviral Disease and Smoking – A Sinister Combination causing Hyperkeratotic Laryngeal Papilloma
title_short Retroviral Disease and Smoking – A Sinister Combination causing Hyperkeratotic Laryngeal Papilloma
title_sort retroviral disease and smoking a sinister combination causing hyperkeratotic laryngeal papilloma
topic Papilloma, Hyperkeratotic
Larynx
HIV
Smoking
url https://www.bjohns.in/journal3/index.php/bjohns/article/view/570
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AT rakeshbs retroviraldiseaseandsmokingasinistercombinationcausinghyperkeratoticlaryngealpapilloma
AT thanzeemunisa retroviraldiseaseandsmokingasinistercombinationcausinghyperkeratoticlaryngealpapilloma
AT kavyas retroviraldiseaseandsmokingasinistercombinationcausinghyperkeratoticlaryngealpapilloma