Utility of salivary biomarker for stress induced by dental treatment

To appropriately and smoothly perform dental treatment, the objective evaluation of patients' stress during treatment is important, for which effective means and methods to measure stress-related markers in simply and noninvasively collectable saliva have been investigated. In this review, sali...

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Main Authors: Kiyoshi Ohura, Tadashige Nozaki, Mitsuko Shinohara, Kiyoshi Daito, Mie Sonomoto, Michiharu Daito
Format: Article
Language:English
Published: Elsevier 2012-02-01
Series:Japanese Dental Science Review
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S1882761611000366
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author Kiyoshi Ohura
Tadashige Nozaki
Mitsuko Shinohara
Kiyoshi Daito
Mie Sonomoto
Michiharu Daito
author_facet Kiyoshi Ohura
Tadashige Nozaki
Mitsuko Shinohara
Kiyoshi Daito
Mie Sonomoto
Michiharu Daito
author_sort Kiyoshi Ohura
collection DOAJ
description To appropriately and smoothly perform dental treatment, the objective evaluation of patients' stress during treatment is important, for which effective means and methods to measure stress-related markers in simply and noninvasively collectable saliva have been investigated. In this review, saliva was collected from pediatric patients before and after treatment, and sIgA, α-amylase, and cortisol were measured to evaluate the stress of dental treatment on them. On analysis of the duration and content of treatment in dental records, the sIgA level showed a clearer response to stress compared to α-amylase and cortisol. Measurement of changes in the salivary sIgA level may be a useful, noninvasive stress evaluation method, and sIgA may serve as a stress marker.
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spelling doaj.art-b5c2f2b76dbb4c64ba9abfb1564367e62022-12-22T03:15:03ZengElsevierJapanese Dental Science Review1882-76162012-02-01481141710.1016/j.jdsr.2011.06.001Utility of salivary biomarker for stress induced by dental treatmentKiyoshi Ohura0Tadashige Nozaki1Mitsuko Shinohara2Kiyoshi Daito3Mie Sonomoto4Michiharu Daito5Department of Pharmacology, Osaka Dental University, 8-1, Kuzuhahanazono-cho, Hirakata, Osaka 573-1121, JapanDepartment of Pharmacology, Osaka Dental University, 8-1, Kuzuhahanazono-cho, Hirakata, Osaka 573-1121, JapanDepartment of Pharmacology, Osaka Dental University, 8-1, Kuzuhahanazono-cho, Hirakata, Osaka 573-1121, JapanDepartment of Pediatric Dentistry, Osaka Dental University, 8-1, Kuzuhahanazono-cho, Hirakata, Osaka 573-1121, JapanDepartment of Pediatric Dentistry, Osaka Dental University, 8-1, Kuzuhahanazono-cho, Hirakata, Osaka 573-1121, JapanDepartment of Pediatric Dentistry, Osaka Dental University, 8-1, Kuzuhahanazono-cho, Hirakata, Osaka 573-1121, JapanTo appropriately and smoothly perform dental treatment, the objective evaluation of patients' stress during treatment is important, for which effective means and methods to measure stress-related markers in simply and noninvasively collectable saliva have been investigated. In this review, saliva was collected from pediatric patients before and after treatment, and sIgA, α-amylase, and cortisol were measured to evaluate the stress of dental treatment on them. On analysis of the duration and content of treatment in dental records, the sIgA level showed a clearer response to stress compared to α-amylase and cortisol. Measurement of changes in the salivary sIgA level may be a useful, noninvasive stress evaluation method, and sIgA may serve as a stress marker.http://www.sciencedirect.com/science/article/pii/S1882761611000366StressSalivaBiomarkerDental treatment
spellingShingle Kiyoshi Ohura
Tadashige Nozaki
Mitsuko Shinohara
Kiyoshi Daito
Mie Sonomoto
Michiharu Daito
Utility of salivary biomarker for stress induced by dental treatment
Japanese Dental Science Review
Stress
Saliva
Biomarker
Dental treatment
title Utility of salivary biomarker for stress induced by dental treatment
title_full Utility of salivary biomarker for stress induced by dental treatment
title_fullStr Utility of salivary biomarker for stress induced by dental treatment
title_full_unstemmed Utility of salivary biomarker for stress induced by dental treatment
title_short Utility of salivary biomarker for stress induced by dental treatment
title_sort utility of salivary biomarker for stress induced by dental treatment
topic Stress
Saliva
Biomarker
Dental treatment
url http://www.sciencedirect.com/science/article/pii/S1882761611000366
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