Lidocaine 2% with adrenaline 1: 80,000 alkalinized with sodium bicarbonate 8.4 % in dental anesthesia
Introduction: The alkalinization of lidocaine has been successful in blocking the inferior dental nerve; however, there are contradictory results regarding its clinical efficacy. Objective: To determine the effect of 2% lidocaine with 1: 80,000 adrenaline alkalinized with 8.4% sodium bicarbonate on...
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| Format: | Article |
| Language: | English |
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Universidad de Ciencias Médicas de La Habana
2020-12-01
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| Series: | Revista Habanera de Ciencias Médicas |
| Subjects: | |
| Online Access: | http://www.revhabanera.sld.cu/index.php/rhab/article/view/2604 |
| _version_ | 1811216039603601408 |
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| author | Victor Chumpitaz-Cerrate Victoria Caldas Cueva Cesar Ivanovish Franco Quino Lesly Karem Chávez Rimache |
| author_facet | Victor Chumpitaz-Cerrate Victoria Caldas Cueva Cesar Ivanovish Franco Quino Lesly Karem Chávez Rimache |
| author_sort | Victor Chumpitaz-Cerrate |
| collection | DOAJ |
| description | Introduction: The alkalinization of lidocaine has been successful in blocking the inferior dental nerve; however, there are contradictory results regarding its clinical efficacy.
Objective: To determine the effect of 2% lidocaine with 1: 80,000 adrenaline alkalinized with 8.4% sodium bicarbonate on inferior dental nerve block.
Material and methods: Experimental, prospective and longitudinal study that comprised 50 patients from the Dental School of the National University of San Marcos. The following solutions were administered for inferior dental nerve block: 2% lidocaine with epinephrine 1: 80,000 alkalinized with 8.4% sodium bicarbonate and 2% lidocaine with 1: 80,000 adrenaline not alkalinized. Pain intensity was evaluated by injection, hemodynamic parameters and anesthetic periods (time of onset of action and duration of the anesthetic effect).
Results: There was a lower pain intensity due to injection in the alkalized lidocaine group (19.16 ± 2.7) compared to the non-alkalinized lidocaine group (22.88 ± 4.2); p=0.02. Likewise, the onset time of action was lower in the alkalized lidocaine group (105.72 ± 9.7) compared to the non-alkalinized lidocaine group (157.52 ± 12.1); p=0.002. However, no significant differences were found in the hemodynamic parameters (p>0.05) and the duration of the anesthetic effect (p=0.114).
Conclusions: Lidocaine 2% with adrenaline 1: 80,000 alkalized with sodium bicarbonate at 8.4% on the block of the inferior dental nerve produces a decrease in pain intensity due to injection and the time of onset of action, compared to the non-alkalinized formulation. However, there are no differences in relation to the hemodynamic parameters or the duration of the anesthetic effect. |
| first_indexed | 2024-04-12T06:31:43Z |
| format | Article |
| id | doaj.art-b5c568f2a83c49f48432da07974c9ca6 |
| institution | Directory Open Access Journal |
| issn | 1729-519X |
| language | English |
| last_indexed | 2024-04-12T06:31:43Z |
| publishDate | 2020-12-01 |
| publisher | Universidad de Ciencias Médicas de La Habana |
| record_format | Article |
| series | Revista Habanera de Ciencias Médicas |
| spelling | doaj.art-b5c568f2a83c49f48432da07974c9ca62022-12-22T03:43:59ZengUniversidad de Ciencias Médicas de La HabanaRevista Habanera de Ciencias Médicas1729-519X2020-12-01196e2604e26041673Lidocaine 2% with adrenaline 1: 80,000 alkalinized with sodium bicarbonate 8.4 % in dental anesthesiaVictor Chumpitaz-Cerrate0Victoria Caldas Cueva1Cesar Ivanovish Franco Quino2Lesly Karem Chávez Rimache3Universidad Científica del Sur. Lima.Universidad Nacional Mayor de San Marcos, Facultad de Odontología. Lima.Universidad Peruana Cayetano Heredia, Escuela de Salud Pública y Administración, Lima.Universidad Nacional Mayor de San Marcos, Facultad de Odontología. Lima.Introduction: The alkalinization of lidocaine has been successful in blocking the inferior dental nerve; however, there are contradictory results regarding its clinical efficacy. Objective: To determine the effect of 2% lidocaine with 1: 80,000 adrenaline alkalinized with 8.4% sodium bicarbonate on inferior dental nerve block. Material and methods: Experimental, prospective and longitudinal study that comprised 50 patients from the Dental School of the National University of San Marcos. The following solutions were administered for inferior dental nerve block: 2% lidocaine with epinephrine 1: 80,000 alkalinized with 8.4% sodium bicarbonate and 2% lidocaine with 1: 80,000 adrenaline not alkalinized. Pain intensity was evaluated by injection, hemodynamic parameters and anesthetic periods (time of onset of action and duration of the anesthetic effect). Results: There was a lower pain intensity due to injection in the alkalized lidocaine group (19.16 ± 2.7) compared to the non-alkalinized lidocaine group (22.88 ± 4.2); p=0.02. Likewise, the onset time of action was lower in the alkalized lidocaine group (105.72 ± 9.7) compared to the non-alkalinized lidocaine group (157.52 ± 12.1); p=0.002. However, no significant differences were found in the hemodynamic parameters (p>0.05) and the duration of the anesthetic effect (p=0.114). Conclusions: Lidocaine 2% with adrenaline 1: 80,000 alkalized with sodium bicarbonate at 8.4% on the block of the inferior dental nerve produces a decrease in pain intensity due to injection and the time of onset of action, compared to the non-alkalinized formulation. However, there are no differences in relation to the hemodynamic parameters or the duration of the anesthetic effect.http://www.revhabanera.sld.cu/index.php/rhab/article/view/2604anestésicos localeslidocaínaalcalinizaciónbicarbonato de sodiosignos vitalesdolor. |
| spellingShingle | Victor Chumpitaz-Cerrate Victoria Caldas Cueva Cesar Ivanovish Franco Quino Lesly Karem Chávez Rimache Lidocaine 2% with adrenaline 1: 80,000 alkalinized with sodium bicarbonate 8.4 % in dental anesthesia Revista Habanera de Ciencias Médicas anestésicos locales lidocaína alcalinización bicarbonato de sodio signos vitales dolor. |
| title | Lidocaine 2% with adrenaline 1: 80,000 alkalinized with sodium bicarbonate 8.4 % in dental anesthesia |
| title_full | Lidocaine 2% with adrenaline 1: 80,000 alkalinized with sodium bicarbonate 8.4 % in dental anesthesia |
| title_fullStr | Lidocaine 2% with adrenaline 1: 80,000 alkalinized with sodium bicarbonate 8.4 % in dental anesthesia |
| title_full_unstemmed | Lidocaine 2% with adrenaline 1: 80,000 alkalinized with sodium bicarbonate 8.4 % in dental anesthesia |
| title_short | Lidocaine 2% with adrenaline 1: 80,000 alkalinized with sodium bicarbonate 8.4 % in dental anesthesia |
| title_sort | lidocaine 2 with adrenaline 1 80 000 alkalinized with sodium bicarbonate 8 4 in dental anesthesia |
| topic | anestésicos locales lidocaína alcalinización bicarbonato de sodio signos vitales dolor. |
| url | http://www.revhabanera.sld.cu/index.php/rhab/article/view/2604 |
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