Developing Targeted Therapies That Exploit Aberrant Histone Ubiquitination in Cancer
Histone ubiquitination is a critical epigenetic mechanism regulating DNA-driven processes such as gene transcription and DNA damage repair. Importantly, the cellular machinery regulating histone ubiquitination is frequently altered in cancers. Moreover, aberrant histone ubiquitination can drive onco...
| Main Authors: | , |
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| Formato: | Artigo |
| Idioma: | English |
| Publicado em: |
MDPI AG
2019-02-01
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| Colecção: | Cells |
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| Acesso em linha: | https://www.mdpi.com/2073-4409/8/2/165 |