Elimination of paternal mitochondria in mouse embryos occurs through autophagic degradation dependent on PARKIN and MUL1

A defining feature of mitochondria is their maternal mode of inheritance. However, little is understood about the cellular mechanism through which paternal mitochondria, delivered from sperm, are eliminated from early mammalian embryos. Autophagy has been implicated in nematodes, but whether this me...

Mô tả đầy đủ

Chi tiết về thư mục
Những tác giả chính: Rebecca Rojansky, Moon-Yong Cha, David C Chan
Định dạng: Bài viết
Ngôn ngữ:English
Được phát hành: eLife Sciences Publications Ltd 2016-11-01
Loạt:eLife
Những chủ đề:
Truy cập trực tuyến:https://elifesciences.org/articles/17896