Elimination of paternal mitochondria in mouse embryos occurs through autophagic degradation dependent on PARKIN and MUL1

Elimination of paternal mitochondria in mouse embryos occurs through autophagic degradation dependent on PARKIN and MUL1

A defining feature of mitochondria is their maternal mode of inheritance. However, little is understood about the cellular mechanism through which paternal mitochondria, delivered from sperm, are eliminated from early mammalian embryos. Autophagy has been implicated in nematodes, but whether this me...

Disgrifiad llawn

Manylion Llyfryddiaeth
Prif Awduron:	Rebecca Rojansky, Moon-Yong Cha, David C Chan
Fformat:	Erthygl
Iaith:	English
Cyhoeddwyd:	eLife Sciences Publications Ltd 2016-11-01
Cyfres:	eLife
Pynciau:	mitochondria mitophagy autophagy
Mynediad Ar-lein:	https://elifesciences.org/articles/17896

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