Elimination of paternal mitochondria in mouse embryos occurs through autophagic degradation dependent on PARKIN and MUL1

Elimination of paternal mitochondria in mouse embryos occurs through autophagic degradation dependent on PARKIN and MUL1

A defining feature of mitochondria is their maternal mode of inheritance. However, little is understood about the cellular mechanism through which paternal mitochondria, delivered from sperm, are eliminated from early mammalian embryos. Autophagy has been implicated in nematodes, but whether this me...

Ausführliche Beschreibung

Bibliographische Detailangaben
Hauptverfasser: Rebecca Rojansky, Moon-Yong Cha, David C Chan
Format: Artikel
Sprache:English
Veröffentlicht: eLife Sciences Publications Ltd 2016-11-01
Schriftenreihe:eLife
Schlagworte:
mitochondria
mitophagy
autophagy
Online Zugang:https://elifesciences.org/articles/17896

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