Elimination of paternal mitochondria in mouse embryos occurs through autophagic degradation dependent on PARKIN and MUL1

Elimination of paternal mitochondria in mouse embryos occurs through autophagic degradation dependent on PARKIN and MUL1

A defining feature of mitochondria is their maternal mode of inheritance. However, little is understood about the cellular mechanism through which paternal mitochondria, delivered from sperm, are eliminated from early mammalian embryos. Autophagy has been implicated in nematodes, but whether this me...

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Dettagli Bibliografici
Autori principali:	Rebecca Rojansky, Moon-Yong Cha, David C Chan
Natura:	Articolo
Lingua:	English
Pubblicazione:	eLife Sciences Publications Ltd 2016-11-01
Serie:	eLife
Soggetti:	mitochondria mitophagy autophagy
Accesso online:	https://elifesciences.org/articles/17896

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