Elimination of paternal mitochondria in mouse embryos occurs through autophagic degradation dependent on PARKIN and MUL1

Elimination of paternal mitochondria in mouse embryos occurs through autophagic degradation dependent on PARKIN and MUL1

A defining feature of mitochondria is their maternal mode of inheritance. However, little is understood about the cellular mechanism through which paternal mitochondria, delivered from sperm, are eliminated from early mammalian embryos. Autophagy has been implicated in nematodes, but whether this me...

Полное описание

Библиографические подробности
Главные авторы:	Rebecca Rojansky, Moon-Yong Cha, David C Chan
Формат:	Статья
Язык:	English
Опубликовано:	eLife Sciences Publications Ltd 2016-11-01
Серии:	eLife
Предметы:	mitochondria mitophagy autophagy
Online-ссылка:	https://elifesciences.org/articles/17896

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