Elimination of paternal mitochondria in mouse embryos occurs through autophagic degradation dependent on PARKIN and MUL1

A defining feature of mitochondria is their maternal mode of inheritance. However, little is understood about the cellular mechanism through which paternal mitochondria, delivered from sperm, are eliminated from early mammalian embryos. Autophagy has been implicated in nematodes, but whether this me...

وصف كامل

التفاصيل البيبلوغرافية
المؤلفون الرئيسيون: Rebecca Rojansky, Moon-Yong Cha, David C Chan
التنسيق: مقال
اللغة:English
منشور في: eLife Sciences Publications Ltd 2016-11-01
سلاسل:eLife
الموضوعات:
الوصول للمادة أونلاين:https://elifesciences.org/articles/17896