Elimination of paternal mitochondria in mouse embryos occurs through autophagic degradation dependent on PARKIN and MUL1

A defining feature of mitochondria is their maternal mode of inheritance. However, little is understood about the cellular mechanism through which paternal mitochondria, delivered from sperm, are eliminated from early mammalian embryos. Autophagy has been implicated in nematodes, but whether this me...

詳細記述

書誌詳細
主要な著者: Rebecca Rojansky, Moon-Yong Cha, David C Chan
フォーマット: 論文
言語:English
出版事項: eLife Sciences Publications Ltd 2016-11-01
シリーズ:eLife
主題:
オンライン・アクセス:https://elifesciences.org/articles/17896