GAP-43 closely interacts with BDNF in hippocampal neurons and is associated with Alzheimer's disease progression

GAP-43 closely interacts with BDNF in hippocampal neurons and is associated with Alzheimer's disease progression

IntroductionGrowth-associated protein 43 (GAP-43) is known as a neuronal plasticity protein because it is widely expressed at high levels in neuronal growth cones during axonal regeneration. GAP-43 expressed in mature adult neurons is functionally important for the neuronal communication of synapses...

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Bibliographic Details
Main Authors: Ye Ji Lee, Ye Ji Jeong, Eun Ji Kang, Beom Seok Kang, Song Hee Lee, You Jin Kim, Seong Su Kang, Sang Won Suh, Eun Hee Ahn
Format: Article
Language:English
Published: Frontiers Media S.A. 2023-04-01
Series:Frontiers in Molecular Neuroscience
Subjects:
brain derived neurotrophic factor (BDNF)
7.8-DHF
growth-associated peptide 43 (GAP43)
molecular interaction
hippocampal neuron
Alzheimer's disease
Online Access:https://www.frontiersin.org/articles/10.3389/fnmol.2023.1150399/full

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