The role of adaptive T cell immunity in atherosclerosis
There is now solid evidence that T cell adaptive immunity is involved in atherogenesis. While initial studies have focused on the pathogenic arm of the immune response, more recent work clearly suggests an important role for several subsets of regulatory T cells in the protection against lesion deve...
| Main Authors: | , , , |
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| Format: | Article |
| Language: | English |
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Elsevier
2009-01-01
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| Series: | Journal of Lipid Research |
| Subjects: | |
| Online Access: | http://www.sciencedirect.com/science/article/pii/S0022227520306404 |
| _version_ | 1818726527237357568 |
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| author | Ziad Mallat Soraya Taleb Hafid Ait-Oufella Alain Tedgui |
| author_facet | Ziad Mallat Soraya Taleb Hafid Ait-Oufella Alain Tedgui |
| author_sort | Ziad Mallat |
| collection | DOAJ |
| description | There is now solid evidence that T cell adaptive immunity is involved in atherogenesis. While initial studies have focused on the pathogenic arm of the immune response, more recent work clearly suggests an important role for several subsets of regulatory T cells in the protection against lesion development. Here, we review the current knowledge on the role of both pathogenic and regulatory adaptive T cell immunity in atherosclerosis, generated mainly from the study of mouse models of the disease. |
| first_indexed | 2024-12-17T21:59:37Z |
| format | Article |
| id | doaj.art-b5cdbba686bb4921af3d0d8f3f376d2c |
| institution | Directory Open Access Journal |
| issn | 0022-2275 |
| language | English |
| last_indexed | 2024-12-17T21:59:37Z |
| publishDate | 2009-01-01 |
| publisher | Elsevier |
| record_format | Article |
| series | Journal of Lipid Research |
| spelling | doaj.art-b5cdbba686bb4921af3d0d8f3f376d2c2022-12-21T21:31:02ZengElsevierJournal of Lipid Research0022-22752009-01-0150S364S369The role of adaptive T cell immunity in atherosclerosisZiad Mallat0Soraya Taleb1Hafid Ait-Oufella2Alain Tedgui3To whom correspondence should be addressed; Paris Cardiovascular Research Center, INSERM and Assistance Publique-Hópitaux de Paris, Hópital Européen Georges Pompidou, 75015 Paris, FranceParis Cardiovascular Research Center, INSERM and Assistance Publique-Hópitaux de Paris, Hópital Européen Georges Pompidou, 75015 Paris, FranceParis Cardiovascular Research Center, INSERM and Assistance Publique-Hópitaux de Paris, Hópital Européen Georges Pompidou, 75015 Paris, FranceParis Cardiovascular Research Center, INSERM and Assistance Publique-Hópitaux de Paris, Hópital Européen Georges Pompidou, 75015 Paris, FranceThere is now solid evidence that T cell adaptive immunity is involved in atherogenesis. While initial studies have focused on the pathogenic arm of the immune response, more recent work clearly suggests an important role for several subsets of regulatory T cells in the protection against lesion development. Here, we review the current knowledge on the role of both pathogenic and regulatory adaptive T cell immunity in atherosclerosis, generated mainly from the study of mouse models of the disease.http://www.sciencedirect.com/science/article/pii/S0022227520306404inflammationlymphocytescytokines |
| spellingShingle | Ziad Mallat Soraya Taleb Hafid Ait-Oufella Alain Tedgui The role of adaptive T cell immunity in atherosclerosis Journal of Lipid Research inflammation lymphocytes cytokines |
| title | The role of adaptive T cell immunity in atherosclerosis |
| title_full | The role of adaptive T cell immunity in atherosclerosis |
| title_fullStr | The role of adaptive T cell immunity in atherosclerosis |
| title_full_unstemmed | The role of adaptive T cell immunity in atherosclerosis |
| title_short | The role of adaptive T cell immunity in atherosclerosis |
| title_sort | role of adaptive t cell immunity in atherosclerosis |
| topic | inflammation lymphocytes cytokines |
| url | http://www.sciencedirect.com/science/article/pii/S0022227520306404 |
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