A novel method to simultaneously record spinal cord electrophysiology and electroencephalography signals
The brain and the spinal cord together make up the central nervous system (CNS). The functions of the human brain have been the focus of neuroscience research for a long time. However, the spinal cord is largely ignored, and the functional interaction of these two parts of the CNS is only partly und...
| Main Authors: | , , , , , , , , , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Elsevier
2021-05-01
|
| Series: | NeuroImage |
| Subjects: | |
| Online Access: | http://www.sciencedirect.com/science/article/pii/S1053811921001695 |
| _version_ | 1818456547673505792 |
|---|---|
| author | Feixue Wang Libo Zhang Lupeng Yue Yuxuan Zeng Qing Zhao Qingjuan Gong Jianbo Zhang Dongyang Liu Xiuying Luo Xiaolei Xia Li Wan Li Hu |
| author_facet | Feixue Wang Libo Zhang Lupeng Yue Yuxuan Zeng Qing Zhao Qingjuan Gong Jianbo Zhang Dongyang Liu Xiuying Luo Xiaolei Xia Li Wan Li Hu |
| author_sort | Feixue Wang |
| collection | DOAJ |
| description | The brain and the spinal cord together make up the central nervous system (CNS). The functions of the human brain have been the focus of neuroscience research for a long time. However, the spinal cord is largely ignored, and the functional interaction of these two parts of the CNS is only partly understood. This study developed a novel method to simultaneously record spinal cord electrophysiology (SCE) and electroencephalography (EEG) signals and validated its performance using a classical resting-state study design with two experimental conditions: eyes-closed (EC) and eyes-open (EO). We recruited nine postherpetic neuralgia patients implanted with a spinal cord stimulator, which was modified to record SCE signals simultaneously with EEG signals. For both EEG and SCE, similar differences were found in delta- and alpha-band oscillations between the EC and EO conditions, and the spectral power of these frequency bands was able to predict EC/EO behaviors. Moreover, causal connectivity analysis suggested a top-down regulation in delta-band oscillations from the brain to the spinal cord. Altogether, this study demonstrates the validity of simultaneous SCE-EEG recording and shows that the novel method is a valuable tool to investigate the brain-spinal interaction. With this method, we can better unite knowledge about the brain and the spinal cord for a deeper understanding of the functions of the whole CNS. |
| first_indexed | 2024-12-14T22:28:24Z |
| format | Article |
| id | doaj.art-b5ce692605b3422192e083a5293a2b45 |
| institution | Directory Open Access Journal |
| issn | 1095-9572 |
| language | English |
| last_indexed | 2024-12-14T22:28:24Z |
| publishDate | 2021-05-01 |
| publisher | Elsevier |
| record_format | Article |
| series | NeuroImage |
| spelling | doaj.art-b5ce692605b3422192e083a5293a2b452022-12-21T22:45:17ZengElsevierNeuroImage1095-95722021-05-01232117892A novel method to simultaneously record spinal cord electrophysiology and electroencephalography signalsFeixue Wang0Libo Zhang1Lupeng Yue2Yuxuan Zeng3Qing Zhao4Qingjuan Gong5Jianbo Zhang6Dongyang Liu7Xiuying Luo8Xiaolei Xia9Li Wan10Li Hu11Department of Pain Management, The State Key Clinical Specialty in Pain Medicine, The Second Affiliated Hospital, Guangzhou Medical University, Guangzhou, China; CAS Key Laboratory of Mental Health, Institute of Psychology, Beijing, China; Department of Psychology, University of Chinese Academy of Sciences, Beijing, China; Research Center of Brain Cognitive Neuroscience, Liaoning Normal University, Dalian, ChinaCAS Key Laboratory of Mental Health, Institute of Psychology, Beijing, China; Department of Psychology, University of Chinese Academy of Sciences, Beijing, ChinaCAS Key Laboratory of Mental Health, Institute of Psychology, Beijing, China; Department of Psychology, University of Chinese Academy of Sciences, Beijing, ChinaCAS Key Laboratory of Mental Health, Institute of Psychology, Beijing, ChinaDepartment of Pain Management, The State Key Clinical Specialty in Pain Medicine, The Second Affiliated Hospital, Guangzhou Medical University, Guangzhou, China; CAS Key Laboratory of Mental Health, Institute of Psychology, Beijing, ChinaDepartment of Pain Management, The State Key Clinical Specialty in Pain Medicine, The Second Affiliated Hospital, Guangzhou Medical University, Guangzhou, ChinaDepartment of Pain Management, The State Key Clinical Specialty in Pain Medicine, The Second Affiliated Hospital, Guangzhou Medical University, Guangzhou, ChinaDepartment of Pain Management, The State Key Clinical Specialty in Pain Medicine, The Second Affiliated Hospital, Guangzhou Medical University, Guangzhou, ChinaDepartment of Pain Management, The State Key Clinical Specialty in Pain Medicine, The Second Affiliated Hospital, Guangzhou Medical University, Guangzhou, ChinaCAS Key Laboratory of Mental Health, Institute of Psychology, Beijing, China; Department of Psychology, University of Chinese Academy of Sciences, Beijing, ChinaDepartment of Pain Management, The State Key Clinical Specialty in Pain Medicine, The Second Affiliated Hospital, Guangzhou Medical University, Guangzhou, China; Corresponding authors.Department of Pain Management, The State Key Clinical Specialty in Pain Medicine, The Second Affiliated Hospital, Guangzhou Medical University, Guangzhou, China; CAS Key Laboratory of Mental Health, Institute of Psychology, Beijing, China; Department of Psychology, University of Chinese Academy of Sciences, Beijing, China; Corresponding authors.The brain and the spinal cord together make up the central nervous system (CNS). The functions of the human brain have been the focus of neuroscience research for a long time. However, the spinal cord is largely ignored, and the functional interaction of these two parts of the CNS is only partly understood. This study developed a novel method to simultaneously record spinal cord electrophysiology (SCE) and electroencephalography (EEG) signals and validated its performance using a classical resting-state study design with two experimental conditions: eyes-closed (EC) and eyes-open (EO). We recruited nine postherpetic neuralgia patients implanted with a spinal cord stimulator, which was modified to record SCE signals simultaneously with EEG signals. For both EEG and SCE, similar differences were found in delta- and alpha-band oscillations between the EC and EO conditions, and the spectral power of these frequency bands was able to predict EC/EO behaviors. Moreover, causal connectivity analysis suggested a top-down regulation in delta-band oscillations from the brain to the spinal cord. Altogether, this study demonstrates the validity of simultaneous SCE-EEG recording and shows that the novel method is a valuable tool to investigate the brain-spinal interaction. With this method, we can better unite knowledge about the brain and the spinal cord for a deeper understanding of the functions of the whole CNS.http://www.sciencedirect.com/science/article/pii/S1053811921001695Spinal cord electrophysiology (SCE)Electroencephalography (EEG)Simultaneous SCE-EEG recordingResting-stateBrain-spinal connection |
| spellingShingle | Feixue Wang Libo Zhang Lupeng Yue Yuxuan Zeng Qing Zhao Qingjuan Gong Jianbo Zhang Dongyang Liu Xiuying Luo Xiaolei Xia Li Wan Li Hu A novel method to simultaneously record spinal cord electrophysiology and electroencephalography signals NeuroImage Spinal cord electrophysiology (SCE) Electroencephalography (EEG) Simultaneous SCE-EEG recording Resting-state Brain-spinal connection |
| title | A novel method to simultaneously record spinal cord electrophysiology and electroencephalography signals |
| title_full | A novel method to simultaneously record spinal cord electrophysiology and electroencephalography signals |
| title_fullStr | A novel method to simultaneously record spinal cord electrophysiology and electroencephalography signals |
| title_full_unstemmed | A novel method to simultaneously record spinal cord electrophysiology and electroencephalography signals |
| title_short | A novel method to simultaneously record spinal cord electrophysiology and electroencephalography signals |
| title_sort | novel method to simultaneously record spinal cord electrophysiology and electroencephalography signals |
| topic | Spinal cord electrophysiology (SCE) Electroencephalography (EEG) Simultaneous SCE-EEG recording Resting-state Brain-spinal connection |
| url | http://www.sciencedirect.com/science/article/pii/S1053811921001695 |
| work_keys_str_mv | AT feixuewang anovelmethodtosimultaneouslyrecordspinalcordelectrophysiologyandelectroencephalographysignals AT libozhang anovelmethodtosimultaneouslyrecordspinalcordelectrophysiologyandelectroencephalographysignals AT lupengyue anovelmethodtosimultaneouslyrecordspinalcordelectrophysiologyandelectroencephalographysignals AT yuxuanzeng anovelmethodtosimultaneouslyrecordspinalcordelectrophysiologyandelectroencephalographysignals AT qingzhao anovelmethodtosimultaneouslyrecordspinalcordelectrophysiologyandelectroencephalographysignals AT qingjuangong anovelmethodtosimultaneouslyrecordspinalcordelectrophysiologyandelectroencephalographysignals AT jianbozhang anovelmethodtosimultaneouslyrecordspinalcordelectrophysiologyandelectroencephalographysignals AT dongyangliu anovelmethodtosimultaneouslyrecordspinalcordelectrophysiologyandelectroencephalographysignals AT xiuyingluo anovelmethodtosimultaneouslyrecordspinalcordelectrophysiologyandelectroencephalographysignals AT xiaoleixia anovelmethodtosimultaneouslyrecordspinalcordelectrophysiologyandelectroencephalographysignals AT liwan anovelmethodtosimultaneouslyrecordspinalcordelectrophysiologyandelectroencephalographysignals AT lihu anovelmethodtosimultaneouslyrecordspinalcordelectrophysiologyandelectroencephalographysignals AT feixuewang novelmethodtosimultaneouslyrecordspinalcordelectrophysiologyandelectroencephalographysignals AT libozhang novelmethodtosimultaneouslyrecordspinalcordelectrophysiologyandelectroencephalographysignals AT lupengyue novelmethodtosimultaneouslyrecordspinalcordelectrophysiologyandelectroencephalographysignals AT yuxuanzeng novelmethodtosimultaneouslyrecordspinalcordelectrophysiologyandelectroencephalographysignals AT qingzhao novelmethodtosimultaneouslyrecordspinalcordelectrophysiologyandelectroencephalographysignals AT qingjuangong novelmethodtosimultaneouslyrecordspinalcordelectrophysiologyandelectroencephalographysignals AT jianbozhang novelmethodtosimultaneouslyrecordspinalcordelectrophysiologyandelectroencephalographysignals AT dongyangliu novelmethodtosimultaneouslyrecordspinalcordelectrophysiologyandelectroencephalographysignals AT xiuyingluo novelmethodtosimultaneouslyrecordspinalcordelectrophysiologyandelectroencephalographysignals AT xiaoleixia novelmethodtosimultaneouslyrecordspinalcordelectrophysiologyandelectroencephalographysignals AT liwan novelmethodtosimultaneouslyrecordspinalcordelectrophysiologyandelectroencephalographysignals AT lihu novelmethodtosimultaneouslyrecordspinalcordelectrophysiologyandelectroencephalographysignals |