Isolated non-compaction of the left ventricular myocardium: a clinical and morphological study

Isolated left ventricular noncompaction (LVNC) in adult patients is a rare form of primary cardiomyopathy. There have been several morphological studies of this condition in which a heart transplantation was performed. Objective: to analyze literature and clinical cases of patients with LVNC, macros...

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Main Authors: I. M. Iljinsky, A. S. Ivanov, N. P. Mozheiko, M. K. Lugovskiy
Format: Article
Language:Russian
Published: Federal Research Center of Transplantology and Artificial Organs named after V.I.Shumakov 2020-04-01
Series:Vestnik Transplantologii i Iskusstvennyh Organov
Subjects:
Online Access:https://journal.transpl.ru/vtio/article/view/1139
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author I. M. Iljinsky
A. S. Ivanov
N. P. Mozheiko
M. K. Lugovskiy
author_facet I. M. Iljinsky
A. S. Ivanov
N. P. Mozheiko
M. K. Lugovskiy
author_sort I. M. Iljinsky
collection DOAJ
description Isolated left ventricular noncompaction (LVNC) in adult patients is a rare form of primary cardiomyopathy. There have been several morphological studies of this condition in which a heart transplantation was performed. Objective: to analyze literature and clinical cases of patients with LVNC, macroscopic and histological data of the removed hearts. Materials and methods. At our center three patients (2 women aged 18 and 31, and 1 man aged 49) were morphologically diagnosed with LVNC had a heart transplant. We retrospectively analyzed the clinical, macroscopic and histological data of the removed hearts in these patients and the results of the transplants performed. Light microscopy of a fixed myocardial preparation stained with hematoxylin and eosin was used for histological examination. Results. A histological examination confirmed the presence of LVMI in these patients. Conclusion. LVMI is a rare disease, that can occur asymptomatic or cause severe congestive heart failure, requiring transplantation.
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spelling doaj.art-b5d0478275cd4e658958b2d298b205942023-03-13T10:37:26ZrusFederal Research Center of Transplantology and Artificial Organs named after V.I.ShumakovVestnik Transplantologii i Iskusstvennyh Organov1995-11912020-04-01221162510.15825/1995-1191-2020-1-16-25843Isolated non-compaction of the left ventricular myocardium: a clinical and morphological studyI. M. Iljinsky0A. S. Ivanov1N. P. Mozheiko2M. K. Lugovskiy3Shumakov National Medical Research Center of Transplantology and Artificial OrgansShumakov National Medical Research Center of Transplantology and Artificial OrgansShumakov National Medical Research Center of Transplantology and Artificial OrgansShumakov National Medical Research Center of Transplantology and Artificial OrgansIsolated left ventricular noncompaction (LVNC) in adult patients is a rare form of primary cardiomyopathy. There have been several morphological studies of this condition in which a heart transplantation was performed. Objective: to analyze literature and clinical cases of patients with LVNC, macroscopic and histological data of the removed hearts. Materials and methods. At our center three patients (2 women aged 18 and 31, and 1 man aged 49) were morphologically diagnosed with LVNC had a heart transplant. We retrospectively analyzed the clinical, macroscopic and histological data of the removed hearts in these patients and the results of the transplants performed. Light microscopy of a fixed myocardial preparation stained with hematoxylin and eosin was used for histological examination. Results. A histological examination confirmed the presence of LVMI in these patients. Conclusion. LVMI is a rare disease, that can occur asymptomatic or cause severe congestive heart failure, requiring transplantation.https://journal.transpl.ru/vtio/article/view/1139isolated left ventricular noncompactionheart transplantation.
spellingShingle I. M. Iljinsky
A. S. Ivanov
N. P. Mozheiko
M. K. Lugovskiy
Isolated non-compaction of the left ventricular myocardium: a clinical and morphological study
Vestnik Transplantologii i Iskusstvennyh Organov
isolated left ventricular noncompaction
heart transplantation.
title Isolated non-compaction of the left ventricular myocardium: a clinical and morphological study
title_full Isolated non-compaction of the left ventricular myocardium: a clinical and morphological study
title_fullStr Isolated non-compaction of the left ventricular myocardium: a clinical and morphological study
title_full_unstemmed Isolated non-compaction of the left ventricular myocardium: a clinical and morphological study
title_short Isolated non-compaction of the left ventricular myocardium: a clinical and morphological study
title_sort isolated non compaction of the left ventricular myocardium a clinical and morphological study
topic isolated left ventricular noncompaction
heart transplantation.
url https://journal.transpl.ru/vtio/article/view/1139
work_keys_str_mv AT imiljinsky isolatednoncompactionoftheleftventricularmyocardiumaclinicalandmorphologicalstudy
AT asivanov isolatednoncompactionoftheleftventricularmyocardiumaclinicalandmorphologicalstudy
AT npmozheiko isolatednoncompactionoftheleftventricularmyocardiumaclinicalandmorphologicalstudy
AT mklugovskiy isolatednoncompactionoftheleftventricularmyocardiumaclinicalandmorphologicalstudy