Amitraz poisoning: Early gastric lavage can prevent life-threatening complications

Amitraz is a worldwide available pesticide of formamidine chemical family, proven to have reversible toxic effects on both animals and humans. Upon intoxication by ingestion, inhalation, or dermal route, it can cause various central nervous system (CNS), CVS, respiratory and gastrointestinal effects...

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Main Authors: Pratti Madhuri, Anirudh Mukherjee, Sukdev Manna, Minakshi Dhar
Format: Article
Language:English
Published: Wolters Kluwer Medknow Publications 2020-01-01
Series:Journal of Family Medicine and Primary Care
Subjects:
Online Access:http://www.jfmpc.com/article.asp?issn=2249-4863;year=2020;volume=9;issue=4;spage=2129;epage=2131;aulast=Madhuri
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author Pratti Madhuri
Anirudh Mukherjee
Sukdev Manna
Minakshi Dhar
author_facet Pratti Madhuri
Anirudh Mukherjee
Sukdev Manna
Minakshi Dhar
author_sort Pratti Madhuri
collection DOAJ
description Amitraz is a worldwide available pesticide of formamidine chemical family, proven to have reversible toxic effects on both animals and humans. Upon intoxication by ingestion, inhalation, or dermal route, it can cause various central nervous system (CNS), CVS, respiratory and gastrointestinal effects, some of which may be life threatening. Because of lack of specific antidote patients are usually managed with supportive and symptomatic management. We describe a case of 36-year-old female patient who presented to us with alleged history of 120 ml amitraz ingestion. She was given early gastric lavage with activated charcoal at emergency along with supportive and symptomatic management. She developed mild CNS depression, bradycardia, miosis, and fluctuating blood pressure. She was managed in intensive care unit and was kept under close hemodynamic monitoring. Her clinical course during hospital stay was uneventful and was successfully discharged without any residual deficits. According to previously published data, this amount of amitraz intoxication could have caused more serious clinical manifestations. This disproportionately less severe clinical manifestation in our patient is attributed to early gastric lavage. Ominous of reducing amitraz-related health hazards lies in the hands of primary health care physicians and regulatory bodies of government.
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spelling doaj.art-b5d2048d4ac0473cb64f59cb25761de32022-12-21T19:28:03ZengWolters Kluwer Medknow PublicationsJournal of Family Medicine and Primary Care2249-48632020-01-01942129213110.4103/jfmpc.jfmpc_1268_19Amitraz poisoning: Early gastric lavage can prevent life-threatening complicationsPratti MadhuriAnirudh MukherjeeSukdev MannaMinakshi DharAmitraz is a worldwide available pesticide of formamidine chemical family, proven to have reversible toxic effects on both animals and humans. Upon intoxication by ingestion, inhalation, or dermal route, it can cause various central nervous system (CNS), CVS, respiratory and gastrointestinal effects, some of which may be life threatening. Because of lack of specific antidote patients are usually managed with supportive and symptomatic management. We describe a case of 36-year-old female patient who presented to us with alleged history of 120 ml amitraz ingestion. She was given early gastric lavage with activated charcoal at emergency along with supportive and symptomatic management. She developed mild CNS depression, bradycardia, miosis, and fluctuating blood pressure. She was managed in intensive care unit and was kept under close hemodynamic monitoring. Her clinical course during hospital stay was uneventful and was successfully discharged without any residual deficits. According to previously published data, this amount of amitraz intoxication could have caused more serious clinical manifestations. This disproportionately less severe clinical manifestation in our patient is attributed to early gastric lavage. Ominous of reducing amitraz-related health hazards lies in the hands of primary health care physicians and regulatory bodies of government.http://www.jfmpc.com/article.asp?issn=2249-4863;year=2020;volume=9;issue=4;spage=2129;epage=2131;aulast=Madhuriamitrazatropineformamidinegastric lavage
spellingShingle Pratti Madhuri
Anirudh Mukherjee
Sukdev Manna
Minakshi Dhar
Amitraz poisoning: Early gastric lavage can prevent life-threatening complications
Journal of Family Medicine and Primary Care
amitraz
atropine
formamidine
gastric lavage
title Amitraz poisoning: Early gastric lavage can prevent life-threatening complications
title_full Amitraz poisoning: Early gastric lavage can prevent life-threatening complications
title_fullStr Amitraz poisoning: Early gastric lavage can prevent life-threatening complications
title_full_unstemmed Amitraz poisoning: Early gastric lavage can prevent life-threatening complications
title_short Amitraz poisoning: Early gastric lavage can prevent life-threatening complications
title_sort amitraz poisoning early gastric lavage can prevent life threatening complications
topic amitraz
atropine
formamidine
gastric lavage
url http://www.jfmpc.com/article.asp?issn=2249-4863;year=2020;volume=9;issue=4;spage=2129;epage=2131;aulast=Madhuri
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AT minakshidhar amitrazpoisoningearlygastriclavagecanpreventlifethreateningcomplications