Coronary Artery Formation Is Driven by Localized Expression of R-spondin3

Coronary Artery Formation Is Driven by Localized Expression of R-spondin3

Coronary arteries are essential to support the heart with oxygen, and coronary heart disease is one of the leading causes of death worldwide. The coronary arteries form at highly stereotyped locations and are derived from the primitive vascular plexus of the heart. How coronary arteries are remodele...

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Bibliographic Details
Main Authors: Fabio Da Silva, Ana Sofia Rocha, Fariba Jian Motamedi, Filippo Massa, Cem Basboga, Harris Morrison, Kay Dietrich Wagner, Andreas Schedl
Format: Article
Language:English
Published: Elsevier 2017-08-01
Series:Cell Reports
Subjects:
coronary artery
coronary formation
endothelial proliferation
R-spondin3
β-catenin
Wnt signaling
Online Access:http://www.sciencedirect.com/science/article/pii/S2211124717310744

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