1-nitropyrene induces ovarian granulosa cell dysfunction through mitochondrial damage

1-nitropyrene induces ovarian granulosa cell dysfunction through mitochondrial damage

Objective To investigate the effect of 1-nitropyrene (1-NP) on the proliferation, cycle progression and sex hormone synthesis of human ovarian granulosa cell line KGN via inducing mitochondrial damage. Methods After KGN cells were treated with 1-NP at different concentrations (0.625, 1.25, 2.5, 5 an...

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Bibliographic Details
Main Authors: CUI Haonan, HE Shijun, WANG Lihong, YANG Wang, YANG Binwei
Format: Article
Language:zho
Published: Editorial Office of Journal of Army Medical University 2023-05-01
Series:陆军军医大学学报
Subjects:
1-nitropyrene
human ovarian granulosa cell line
cycle arrest
sex hormone
mitochondria
Online Access:http://aammt.tmmu.edu.cn/html/202210115.htm

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