Epithelioid leiomyosarcoma of the uterus and the diagnostic challenge in diagnosing it on small biopsy
Epithelioid leiomyosarcoma of the uterus is a rare soft-tissue tumor of the pelvis with <1% cases. It can be asymptomatic or can reach an enormous size, resulting in chronic pelvic pain, postmenopausal bleeding, or may cause bowel and bladder dysfunction. The diagnostic dilemma arises especially...
| Main Authors: | , , , |
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| Format: | Article |
| Language: | English |
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Wolters Kluwer Medknow Publications
2022-01-01
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| Series: | Journal of Mid-Life Health |
| Subjects: | |
| Online Access: | http://www.jmidlifehealth.org/article.asp?issn=0976-7800;year=2022;volume=13;issue=3;spage=241;epage=243;aulast=Aden |
| _version_ | 1828014051029942272 |
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| author | Durre Aden Sufian Zaheer Shruti Singh Sunil Ranga |
| author_facet | Durre Aden Sufian Zaheer Shruti Singh Sunil Ranga |
| author_sort | Durre Aden |
| collection | DOAJ |
| description | Epithelioid leiomyosarcoma of the uterus is a rare soft-tissue tumor of the pelvis with <1% cases. It can be asymptomatic or can reach an enormous size, resulting in chronic pelvic pain, postmenopausal bleeding, or may cause bowel and bladder dysfunction. The diagnostic dilemma arises especially when they have epithelioid morphology. This case is being presented because of its rare incidence along with the diagnostic dilemma it presented due to epithelioid morphology which is a very rare presentation, especially challenging on small biopsies. This case also highlights the usefulness of immunohistochemical markers, such as WT1, p53, and p16, which has important diagnostic as well as prognostic values in rare variants of usual tumors. Leiomyosarcoma per se is a highly aggressive tumor, therefore, timely diagnosis and management are advised. |
| first_indexed | 2024-04-10T09:54:35Z |
| format | Article |
| id | doaj.art-b5daadd8ac454cd2a316f683ce30144f |
| institution | Directory Open Access Journal |
| issn | 0976-7800 0976-7819 |
| language | English |
| last_indexed | 2024-04-10T09:54:35Z |
| publishDate | 2022-01-01 |
| publisher | Wolters Kluwer Medknow Publications |
| record_format | Article |
| series | Journal of Mid-Life Health |
| spelling | doaj.art-b5daadd8ac454cd2a316f683ce30144f2023-02-16T12:42:00ZengWolters Kluwer Medknow PublicationsJournal of Mid-Life Health0976-78000976-78192022-01-0113324124310.4103/jmh.jmh_36_22Epithelioid leiomyosarcoma of the uterus and the diagnostic challenge in diagnosing it on small biopsyDurre AdenSufian ZaheerShruti SinghSunil RangaEpithelioid leiomyosarcoma of the uterus is a rare soft-tissue tumor of the pelvis with <1% cases. It can be asymptomatic or can reach an enormous size, resulting in chronic pelvic pain, postmenopausal bleeding, or may cause bowel and bladder dysfunction. The diagnostic dilemma arises especially when they have epithelioid morphology. This case is being presented because of its rare incidence along with the diagnostic dilemma it presented due to epithelioid morphology which is a very rare presentation, especially challenging on small biopsies. This case also highlights the usefulness of immunohistochemical markers, such as WT1, p53, and p16, which has important diagnostic as well as prognostic values in rare variants of usual tumors. Leiomyosarcoma per se is a highly aggressive tumor, therefore, timely diagnosis and management are advised.http://www.jmidlifehealth.org/article.asp?issn=0976-7800;year=2022;volume=13;issue=3;spage=241;epage=243;aulast=Adenepithelioid leiomyosarcomaneoplasmpelvisuterus |
| spellingShingle | Durre Aden Sufian Zaheer Shruti Singh Sunil Ranga Epithelioid leiomyosarcoma of the uterus and the diagnostic challenge in diagnosing it on small biopsy Journal of Mid-Life Health epithelioid leiomyosarcoma neoplasm pelvis uterus |
| title | Epithelioid leiomyosarcoma of the uterus and the diagnostic challenge in diagnosing it on small biopsy |
| title_full | Epithelioid leiomyosarcoma of the uterus and the diagnostic challenge in diagnosing it on small biopsy |
| title_fullStr | Epithelioid leiomyosarcoma of the uterus and the diagnostic challenge in diagnosing it on small biopsy |
| title_full_unstemmed | Epithelioid leiomyosarcoma of the uterus and the diagnostic challenge in diagnosing it on small biopsy |
| title_short | Epithelioid leiomyosarcoma of the uterus and the diagnostic challenge in diagnosing it on small biopsy |
| title_sort | epithelioid leiomyosarcoma of the uterus and the diagnostic challenge in diagnosing it on small biopsy |
| topic | epithelioid leiomyosarcoma neoplasm pelvis uterus |
| url | http://www.jmidlifehealth.org/article.asp?issn=0976-7800;year=2022;volume=13;issue=3;spage=241;epage=243;aulast=Aden |
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