Correlation of mutated gene and signalling pathways in ASD
Autism is a complicated spectrum of neurodevelopmental illnesses characterized by repetitive and constrained behaviors and interests, as well as social interaction and communication difficulties that are first shown in infancy. More than 18 million Indians, according to the National Health Portal of...
| Main Authors: | , |
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| Format: | Article |
| Language: | English |
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Elsevier
2023-06-01
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| Series: | IBRO Neuroscience Reports |
| Subjects: | |
| Online Access: | http://www.sciencedirect.com/science/article/pii/S2667242123000295 |
| _version_ | 1797804551833649152 |
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| author | Madhavi Apte Aayush Kumar |
| author_facet | Madhavi Apte Aayush Kumar |
| author_sort | Madhavi Apte |
| collection | DOAJ |
| description | Autism is a complicated spectrum of neurodevelopmental illnesses characterized by repetitive and constrained behaviors and interests, as well as social interaction and communication difficulties that are first shown in infancy. More than 18 million Indians, according to the National Health Portal of India, and 1 in 160 children worldwide, according to the WHO, are diagnosed with autism spectrum disorders. This review aims to discuss the complex genetic architecture that underlies autism and summarizes the role of proteins likely to play in the development of autism. We also consider how genetic mutations can affect convergent signaling pathways and hinder the development of brain circuitry and the role of cognition development and theory of mind with Cognition-behavior therapy benefits in autism. |
| first_indexed | 2024-03-13T05:38:53Z |
| format | Article |
| id | doaj.art-b5dd8849d43c4c65b55182d89efa3fd0 |
| institution | Directory Open Access Journal |
| issn | 2667-2421 |
| language | English |
| last_indexed | 2024-03-13T05:38:53Z |
| publishDate | 2023-06-01 |
| publisher | Elsevier |
| record_format | Article |
| series | IBRO Neuroscience Reports |
| spelling | doaj.art-b5dd8849d43c4c65b55182d89efa3fd02023-06-14T04:34:42ZengElsevierIBRO Neuroscience Reports2667-24212023-06-0114384392Correlation of mutated gene and signalling pathways in ASDMadhavi Apte0Aayush Kumar1Quality Assurance and Pharmacognosy and Phytochemistry, SVKM’s Dr. Bhanuben Nanavati College of Pharmacy, Vile Parle, 400056 Mumbai, India; Correspondence to: SVKM’s Dr. Bhanuben Nanavati College of Pharmacy, Mithibai Campus, V.M. Road, Vile Parle West, 400056 Mumbai, India.Quality Assurance, SVKM’s Dr. Bhanuben Nanavati College of Pharmacy, Vile Parle, 400056 Mumbai, IndiaAutism is a complicated spectrum of neurodevelopmental illnesses characterized by repetitive and constrained behaviors and interests, as well as social interaction and communication difficulties that are first shown in infancy. More than 18 million Indians, according to the National Health Portal of India, and 1 in 160 children worldwide, according to the WHO, are diagnosed with autism spectrum disorders. This review aims to discuss the complex genetic architecture that underlies autism and summarizes the role of proteins likely to play in the development of autism. We also consider how genetic mutations can affect convergent signaling pathways and hinder the development of brain circuitry and the role of cognition development and theory of mind with Cognition-behavior therapy benefits in autism.http://www.sciencedirect.com/science/article/pii/S2667242123000295AutismGeneticsSignaling pathwayGene mutationCognition developmentTheory of mind |
| spellingShingle | Madhavi Apte Aayush Kumar Correlation of mutated gene and signalling pathways in ASD IBRO Neuroscience Reports Autism Genetics Signaling pathway Gene mutation Cognition development Theory of mind |
| title | Correlation of mutated gene and signalling pathways in ASD |
| title_full | Correlation of mutated gene and signalling pathways in ASD |
| title_fullStr | Correlation of mutated gene and signalling pathways in ASD |
| title_full_unstemmed | Correlation of mutated gene and signalling pathways in ASD |
| title_short | Correlation of mutated gene and signalling pathways in ASD |
| title_sort | correlation of mutated gene and signalling pathways in asd |
| topic | Autism Genetics Signaling pathway Gene mutation Cognition development Theory of mind |
| url | http://www.sciencedirect.com/science/article/pii/S2667242123000295 |
| work_keys_str_mv | AT madhaviapte correlationofmutatedgeneandsignallingpathwaysinasd AT aayushkumar correlationofmutatedgeneandsignallingpathwaysinasd |