The role of protein-derived free radicals as intermediaries of oxidative processes

The fact that proteins are the main target of reactive species formed in the cells and extracellular fluids has led to the realization of a great deal of research devoted to revealing the molecular and biological consequences associated with the presence of intermediary protein radicals. This review...

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Main Authors: López-Alarcón Camilo, Arenas Andrea, Lissi Eduardo, Silva Eduardo
Format: Article
Language:English
Published: De Gruyter 2014-05-01
Series:Biomolecular Concepts
Subjects:
Online Access:https://doi.org/10.1515/bmc-2014-0004
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author López-Alarcón Camilo
Arenas Andrea
Lissi Eduardo
Silva Eduardo
author_facet López-Alarcón Camilo
Arenas Andrea
Lissi Eduardo
Silva Eduardo
author_sort López-Alarcón Camilo
collection DOAJ
description The fact that proteins are the main target of reactive species formed in the cells and extracellular fluids has led to the realization of a great deal of research devoted to revealing the molecular and biological consequences associated with the presence of intermediary protein radicals. This review article describes and comments upon the main chemical pathways involving primary proteic radicals.
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spelling doaj.art-b5e257bfd70843359ae74d62ae8151e72022-12-21T21:55:34ZengDe GruyterBiomolecular Concepts1868-50211868-503X2014-05-015211913010.1515/bmc-2014-0004The role of protein-derived free radicals as intermediaries of oxidative processesLópez-Alarcón Camilo0Arenas AndreaLissi Eduardo1Silva Eduardo2Departamento de Farmacia, Facultad de Química, Pontificia Universidad Católica de Chile, Vicuña Mackenna 4860, Santiago 7820436, ChileFacultad de Química y Biología, Universidad de Santiago de Chile, Santiago, ChileDepartamento de Química Física, Facultad de Química, Pontificia Universidad Católica de Chile, ChileThe fact that proteins are the main target of reactive species formed in the cells and extracellular fluids has led to the realization of a great deal of research devoted to revealing the molecular and biological consequences associated with the presence of intermediary protein radicals. This review article describes and comments upon the main chemical pathways involving primary proteic radicals.https://doi.org/10.1515/bmc-2014-0004carbonylschain reactionsprotein-derived free radicalsreactive speciesrepair mechanisms
spellingShingle López-Alarcón Camilo
Arenas Andrea
Lissi Eduardo
Silva Eduardo
The role of protein-derived free radicals as intermediaries of oxidative processes
Biomolecular Concepts
carbonyls
chain reactions
protein-derived free radicals
reactive species
repair mechanisms
title The role of protein-derived free radicals as intermediaries of oxidative processes
title_full The role of protein-derived free radicals as intermediaries of oxidative processes
title_fullStr The role of protein-derived free radicals as intermediaries of oxidative processes
title_full_unstemmed The role of protein-derived free radicals as intermediaries of oxidative processes
title_short The role of protein-derived free radicals as intermediaries of oxidative processes
title_sort role of protein derived free radicals as intermediaries of oxidative processes
topic carbonyls
chain reactions
protein-derived free radicals
reactive species
repair mechanisms
url https://doi.org/10.1515/bmc-2014-0004
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