Young‐onset diabetes patients in Thailand: Data from Thai Type 1 Diabetes and Diabetes diagnosed Age before 30 years Registry, Care and Network (T1DDAR CN)
ABSTRACT Aims/Introduction There is a lack of current information regarding young‐onset diabetes in Thailand. Thus, the objectives of this study were to describe the types of diabetes, the clinical characteristics, the treatment regimens and achievement of glycemic control in Thai patients with youn...
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| Format: | Article |
| Language: | English |
| Published: |
Wiley
2022-05-01
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| Series: | Journal of Diabetes Investigation |
| Subjects: | |
| Online Access: | https://doi.org/10.1111/jdi.13732 |
| _version_ | 1811338541661159424 |
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| author | Prapai Dejkhamron Jeerunda Santiprabhob Supawadee Likitmaskul Chaicharn Deerochanawong Petch Rawdaree Thipaporn Tharavanij Sirimon Reutrakul Chawkaew Kongkanka Chittiwat Suprasongsin Nawaporn Numbenjapon Taninee Sahakitrungruang Raweewan Lertwattanarak Pontipa Engkakul Apiradee Sriwijitkamol Manassawee Korwutthikulrangsri Rattana Leelawattana Mattabhorn Phimphilai Somkiat Potisat Panthep Khananuraksa Kemarasami Kunsuikmengrai Wannee Nitiyanant for the Thai Type 1 Diabetes and Diabetes diagnosed Age before 30 years Registry, Care and Network (T1DDAR CN) |
| author_facet | Prapai Dejkhamron Jeerunda Santiprabhob Supawadee Likitmaskul Chaicharn Deerochanawong Petch Rawdaree Thipaporn Tharavanij Sirimon Reutrakul Chawkaew Kongkanka Chittiwat Suprasongsin Nawaporn Numbenjapon Taninee Sahakitrungruang Raweewan Lertwattanarak Pontipa Engkakul Apiradee Sriwijitkamol Manassawee Korwutthikulrangsri Rattana Leelawattana Mattabhorn Phimphilai Somkiat Potisat Panthep Khananuraksa Kemarasami Kunsuikmengrai Wannee Nitiyanant for the Thai Type 1 Diabetes and Diabetes diagnosed Age before 30 years Registry, Care and Network (T1DDAR CN) |
| author_sort | Prapai Dejkhamron |
| collection | DOAJ |
| description | ABSTRACT Aims/Introduction There is a lack of current information regarding young‐onset diabetes in Thailand. Thus, the objectives of this study were to describe the types of diabetes, the clinical characteristics, the treatment regimens and achievement of glycemic control in Thai patients with young‐onset diabetes. Materials and Methods Data of 2,844 patients with diabetes onset before 30 years‐of‐age were retrospectively reviewed from a diabetes registry comprising 31 hospitals in Thailand. Gestational diabetes was excluded. Results Based on clinical criteria, type 1 diabetes was identified in 62.6% of patients, type 2 diabetes in 30.7%, neonatal diabetes in 0.8%, other monogenic diabetes in 1.7%, secondary diabetes in 3.0%, genetic syndromes associated with diabetes in 0.9% and other types of diabetes in 0.4%. Type 1 diabetes accounted for 72.3% of patients with age of onset <20 years. The proportion of type 2 diabetes was 61.0% of patients with age of onset from 20 to <30 years. Intensive insulin treatment was prescribed to 55.2% of type 1 diabetes patients. Oral antidiabetic agent alone was used in 50.8% of type 2 diabetes patients, whereas 44.1% received insulin treatment. Most monogenic diabetes, secondary diabetes and genetic syndromes associated with diabetes required insulin treatment. Achievement of glycemic control was identified in 12.4% of type 1 diabetes patients, 30% of type 2 diabetes patients, 36.4% of neonatal diabetes patients, 28.3% of other monogenic diabetes patients, 45.6% of secondary diabetes patients and 28% of genetic syndromes associated with diabetes patients. Conclusion In this registry, type 1 diabetes remains the most common type and the prevalence of type 2 diabetes increases with age. The majority of patients did not achieve the glycemic target, especially type 1 diabetes patients. |
| first_indexed | 2024-04-13T18:13:35Z |
| format | Article |
| id | doaj.art-b5e4af8feb9d42d582a9ddf8dccf782d |
| institution | Directory Open Access Journal |
| issn | 2040-1116 2040-1124 |
| language | English |
| last_indexed | 2024-04-13T18:13:35Z |
| publishDate | 2022-05-01 |
| publisher | Wiley |
| record_format | Article |
| series | Journal of Diabetes Investigation |
| spelling | doaj.art-b5e4af8feb9d42d582a9ddf8dccf782d2022-12-22T02:35:49ZengWileyJournal of Diabetes Investigation2040-11162040-11242022-05-0113579680910.1111/jdi.13732Young‐onset diabetes patients in Thailand: Data from Thai Type 1 Diabetes and Diabetes diagnosed Age before 30 years Registry, Care and Network (T1DDAR CN)Prapai Dejkhamron0Jeerunda Santiprabhob1Supawadee Likitmaskul2Chaicharn Deerochanawong3Petch Rawdaree4Thipaporn Tharavanij5Sirimon Reutrakul6Chawkaew Kongkanka7Chittiwat Suprasongsin8Nawaporn Numbenjapon9Taninee Sahakitrungruang10Raweewan Lertwattanarak11Pontipa Engkakul12Apiradee Sriwijitkamol13Manassawee Korwutthikulrangsri14Rattana Leelawattana15Mattabhorn Phimphilai16Somkiat Potisat17Panthep Khananuraksa18Kemarasami Kunsuikmengrai19Wannee Nitiyanant20for the Thai Type 1 Diabetes and Diabetes diagnosed Age before 30 years Registry, Care and Network (T1DDAR CN)Division of Endocrinology and Metabolism Department of Pediatrics Faculty of Medicine Chiang Mai University Chiang Mai ThailandSiriraj Diabetes Center Faculty of Medicine Siriraj Hospital Mahidol University Bangkok ThailandSiriraj Diabetes Center Faculty of Medicine Siriraj Hospital Mahidol University Bangkok ThailandDivision of Endocrinology and Metabolism Department of Medicine College of Medicine Rajavithi Hospital Rangsit University Bangkok ThailandDivision of Endocrinology and Metabolism Department of Internal Medicine Faculty of Medicine Vajira Hospital Navamindradhiraj University Bangkok ThailandEndocrine and Metabolism Unit Department of Internal Medicine Faculty of Medicine Thammasat University Pathum Thani ThailandDivision of Endocrinology and Metabolism Department of Medicine Faculty of Medicine Ramathibodi Hospital Mahidol University Bangkok ThailandEndocrinology and Metabolism Unit Department of Pediatrics Queen Sirikit National Institute of Child Health Bangkok ThailandResearch Center Faculty of Medicine Ramathibodi Hospital Mahidol University Bangkok ThailandDivision of Endocrinology, Diabetes, and Metabolism Department of Pediatrics Phramongkutklao Hospital and College of Medicine Bangkok ThailandDivision of Pediatric Endocrinology Department of Pediatrics Faculty of Medicine Chulalongkorn University Bangkok ThailandSiriraj Diabetes Center Faculty of Medicine Siriraj Hospital Mahidol University Bangkok ThailandEndocrinology and Metabolism Unit Department of Pediatrics Faculty of Medicine Thammasat University Pathum Thani ThailandSiriraj Diabetes Center Faculty of Medicine Siriraj Hospital Mahidol University Bangkok ThailandDivision of Endocrinology and Metabolism Department of Pediatrics Faculty of Medicine Ramathibodi Hospital Mahidol University Bangkok ThailandDivision of Endocrinology and Metabolism Department of Medicine Faculty of Medicine Prince of Songkla University Songkla ThailandNorthern Diabetes Center Faculty of Medicine Chiang Mai University Chiang Mai ThailandDepartment of Medical Services Ministry of Public Health Nonthaburi ThailandNational Health Security Office (NHSO) of Thailand Bangkok ThailandNational Health Security Office (NHSO) of Thailand Bangkok ThailandSiriraj Diabetes Center Faculty of Medicine Siriraj Hospital Mahidol University Bangkok ThailandABSTRACT Aims/Introduction There is a lack of current information regarding young‐onset diabetes in Thailand. Thus, the objectives of this study were to describe the types of diabetes, the clinical characteristics, the treatment regimens and achievement of glycemic control in Thai patients with young‐onset diabetes. Materials and Methods Data of 2,844 patients with diabetes onset before 30 years‐of‐age were retrospectively reviewed from a diabetes registry comprising 31 hospitals in Thailand. Gestational diabetes was excluded. Results Based on clinical criteria, type 1 diabetes was identified in 62.6% of patients, type 2 diabetes in 30.7%, neonatal diabetes in 0.8%, other monogenic diabetes in 1.7%, secondary diabetes in 3.0%, genetic syndromes associated with diabetes in 0.9% and other types of diabetes in 0.4%. Type 1 diabetes accounted for 72.3% of patients with age of onset <20 years. The proportion of type 2 diabetes was 61.0% of patients with age of onset from 20 to <30 years. Intensive insulin treatment was prescribed to 55.2% of type 1 diabetes patients. Oral antidiabetic agent alone was used in 50.8% of type 2 diabetes patients, whereas 44.1% received insulin treatment. Most monogenic diabetes, secondary diabetes and genetic syndromes associated with diabetes required insulin treatment. Achievement of glycemic control was identified in 12.4% of type 1 diabetes patients, 30% of type 2 diabetes patients, 36.4% of neonatal diabetes patients, 28.3% of other monogenic diabetes patients, 45.6% of secondary diabetes patients and 28% of genetic syndromes associated with diabetes patients. Conclusion In this registry, type 1 diabetes remains the most common type and the prevalence of type 2 diabetes increases with age. The majority of patients did not achieve the glycemic target, especially type 1 diabetes patients.https://doi.org/10.1111/jdi.13732PatientsThai Type 1 Diabetes and Diabetes diagnosed Age before 30 years Registry, Care and NetworkYoung‐onset diabetes |
| spellingShingle | Prapai Dejkhamron Jeerunda Santiprabhob Supawadee Likitmaskul Chaicharn Deerochanawong Petch Rawdaree Thipaporn Tharavanij Sirimon Reutrakul Chawkaew Kongkanka Chittiwat Suprasongsin Nawaporn Numbenjapon Taninee Sahakitrungruang Raweewan Lertwattanarak Pontipa Engkakul Apiradee Sriwijitkamol Manassawee Korwutthikulrangsri Rattana Leelawattana Mattabhorn Phimphilai Somkiat Potisat Panthep Khananuraksa Kemarasami Kunsuikmengrai Wannee Nitiyanant for the Thai Type 1 Diabetes and Diabetes diagnosed Age before 30 years Registry, Care and Network (T1DDAR CN) Young‐onset diabetes patients in Thailand: Data from Thai Type 1 Diabetes and Diabetes diagnosed Age before 30 years Registry, Care and Network (T1DDAR CN) Journal of Diabetes Investigation Patients Thai Type 1 Diabetes and Diabetes diagnosed Age before 30 years Registry, Care and Network Young‐onset diabetes |
| title | Young‐onset diabetes patients in Thailand: Data from Thai Type 1 Diabetes and Diabetes diagnosed Age before 30 years Registry, Care and Network (T1DDAR CN) |
| title_full | Young‐onset diabetes patients in Thailand: Data from Thai Type 1 Diabetes and Diabetes diagnosed Age before 30 years Registry, Care and Network (T1DDAR CN) |
| title_fullStr | Young‐onset diabetes patients in Thailand: Data from Thai Type 1 Diabetes and Diabetes diagnosed Age before 30 years Registry, Care and Network (T1DDAR CN) |
| title_full_unstemmed | Young‐onset diabetes patients in Thailand: Data from Thai Type 1 Diabetes and Diabetes diagnosed Age before 30 years Registry, Care and Network (T1DDAR CN) |
| title_short | Young‐onset diabetes patients in Thailand: Data from Thai Type 1 Diabetes and Diabetes diagnosed Age before 30 years Registry, Care and Network (T1DDAR CN) |
| title_sort | young onset diabetes patients in thailand data from thai type 1 diabetes and diabetes diagnosed age before 30 years registry care and network t1ddar cn |
| topic | Patients Thai Type 1 Diabetes and Diabetes diagnosed Age before 30 years Registry, Care and Network Young‐onset diabetes |
| url | https://doi.org/10.1111/jdi.13732 |
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