Polypharmacy and relapse of schizophrenia: are they related?
Introduction Polypharmacy can be the cause of deliberate discontinuation of medication and consequent relapse of schizophrenia. Objectives To establish the one-year rate of relapse in the patients with schizophrenia with regard to monotherapy or polypharmacy. Methods The sample of all hospitalize...
| Main Authors: | , , |
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| Format: | Article |
| Language: | English |
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Cambridge University Press
2022-06-01
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| Series: | European Psychiatry |
| Subjects: | |
| Online Access: | https://www.cambridge.org/core/product/identifier/S0924933822019757/type/journal_article |
| _version_ | 1797616524638289920 |
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| author | R. Softic S. Osmanovic N. Becarevic |
| author_facet | R. Softic S. Osmanovic N. Becarevic |
| author_sort | R. Softic |
| collection | DOAJ |
| description |
Introduction
Polypharmacy can be the cause of deliberate discontinuation of medication and consequent relapse of schizophrenia.
Objectives
To establish the one-year rate of relapse in the patients with schizophrenia with regard to monotherapy or polypharmacy.
Methods
The sample of all hospitalized patients with schizophrenia in a five-year period was analyzed. Descriptive statistics were used.
Results
Total of 87 participants (57 women), the median age was 43 years. Antipsychotic monotherapy was used in 31 (35.6%) of the participants. In one year period, 32 (36.8%) of all participants had a relapse. Prior to relapse, significantly more participants were treated with polypharmacy (p<0,05).
Conclusions
Antipsychotic polypharmacy is related to a higher rate of relapse in patients with schizophrenia.
Disclosure
No significant relationships.
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| first_indexed | 2024-03-11T07:42:27Z |
| format | Article |
| id | doaj.art-b5e5118126f64cc0b6f86ed6b7176c66 |
| institution | Directory Open Access Journal |
| issn | 0924-9338 1778-3585 |
| language | English |
| last_indexed | 2024-03-11T07:42:27Z |
| publishDate | 2022-06-01 |
| publisher | Cambridge University Press |
| record_format | Article |
| series | European Psychiatry |
| spelling | doaj.art-b5e5118126f64cc0b6f86ed6b7176c662023-11-17T05:08:23ZengCambridge University PressEuropean Psychiatry0924-93381778-35852022-06-0165S765S76510.1192/j.eurpsy.2022.1975Polypharmacy and relapse of schizophrenia: are they related?R. Softic0S. Osmanovic1N. Becarevic2University Clinical Center Tuzla, Of Psychiatry, Tuzla, Bosnia and HerzegovinaHealth Center Brčko, Of Psychiatry, Brčko, Bosnia and HerzegovinaUniversity Clinical Center Tuzla, Of Psychiatry, Tuzla, Bosnia and Herzegovina Introduction Polypharmacy can be the cause of deliberate discontinuation of medication and consequent relapse of schizophrenia. Objectives To establish the one-year rate of relapse in the patients with schizophrenia with regard to monotherapy or polypharmacy. Methods The sample of all hospitalized patients with schizophrenia in a five-year period was analyzed. Descriptive statistics were used. Results Total of 87 participants (57 women), the median age was 43 years. Antipsychotic monotherapy was used in 31 (35.6%) of the participants. In one year period, 32 (36.8%) of all participants had a relapse. Prior to relapse, significantly more participants were treated with polypharmacy (p<0,05). Conclusions Antipsychotic polypharmacy is related to a higher rate of relapse in patients with schizophrenia. Disclosure No significant relationships. https://www.cambridge.org/core/product/identifier/S0924933822019757/type/journal_articleschizophréniaRelapsePolypharmacy |
| spellingShingle | R. Softic S. Osmanovic N. Becarevic Polypharmacy and relapse of schizophrenia: are they related? European Psychiatry schizophrénia Relapse Polypharmacy |
| title | Polypharmacy and relapse of schizophrenia: are they related? |
| title_full | Polypharmacy and relapse of schizophrenia: are they related? |
| title_fullStr | Polypharmacy and relapse of schizophrenia: are they related? |
| title_full_unstemmed | Polypharmacy and relapse of schizophrenia: are they related? |
| title_short | Polypharmacy and relapse of schizophrenia: are they related? |
| title_sort | polypharmacy and relapse of schizophrenia are they related |
| topic | schizophrénia Relapse Polypharmacy |
| url | https://www.cambridge.org/core/product/identifier/S0924933822019757/type/journal_article |
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