| Summary: | This study attempted to investigate the effect of sandblasting and H<sub>2</sub>O<sub>2</sub> treatments on the microshear bond strength of two commercially available resin cements. A total of 90 cube-shaped specimens of commercially pure titanium (cp-Ti) were divided into two groups of Panavia and MHA cements (<i>n</i> = 45). Samples of the Panavia group were randomly divided into three subgroups of 15 samples, including subgroups (no treatment, aluminum oxide sandblasting, and immersion in 35% hydrogen peroxide solution with halogen light). Once the treatment was completed, Panavia V5 was applied on the cp-Ti surface by a Tygon tube. The 45 specimens of the MHA cement group were randomly divided into three subgroups (<i>n</i> = 15) similarly to the Panavia group. Then, the MHA was applied on the surface of cp-Ti. A universal testing machine was used to measure and examine the microshear bond strength of cement to cp-Ti subsequent to the step of thermocycling. According to results, in the Panavia cement group, the SBS of sandblasting treatment was significantly higher than that of the H<sub>2</sub>O<sub>2</sub> treatment subgroup (<i>p</i> < 0.05), which displayed a significantly higher SBS than that of the no-treatment subgroup (<i>p</i> < 0.001). In regard to the MHA group, the SBS of the H<sub>2</sub>O<sub>2</sub> treatment subgroup was significantly lower than that of the sandblasting treatment subgroup (<i>p</i> < 0.001), whereas there were no significant differences between the SBS of the no treatment and H<sub>2</sub>O<sub>2</sub> treatment subgroups (<i>p</i> = 0.35). Considering the comparison between Panavia and MHA cases, there were no significant differences observed among the no-treatment subgroups (<i>p</i> = 0.34), as well as the sandblasting treatment subgroups (<i>p</i> = 0.67), while the SBS of the H<sub>2</sub>O<sub>2</sub> treatment subgroup in Panavia cement was higher than that of the H<sub>2</sub>O<sub>2</sub> subgroup in MHA cement (<i>p</i> < 0.001). In conclusion, in both Panavia V5 and MHA cements, sandblasting treatment could improve the bond strength between the titanium surface. However, H<sub>2</sub>O<sub>2</sub> treatment proved to be capable of enhancing the bond strength of Panavia V5 cement without causing any positive effects on the bond strength of MHA cement.
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