Causal association of epigenetic aging and COVID-19 severity and susceptibility: A bidirectional Mendelian randomization study

Causal association of epigenetic aging and COVID-19 severity and susceptibility: A bidirectional Mendelian randomization study

Observational data from China, the United States, France, and Italy suggest that chronological age is an adverse COVID-19 outcome risk factor, with older patients having a higher severity and mortality rate than younger patients. Most studies have gotten the same view. However, the role of aging in...

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Bibliographic Details
Main Authors: Wenchang Xu, Fengjun Zhang, Yingzhou Shi, Yuanzhen Chen, Bin Shi, Gongchang Yu
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-09-01
Series:Frontiers in Medicine
Subjects:
Mendelian randomization
aging
COVID-19
epigenetic age
telomere length
genome-wide association study (GWAS)
Online Access:https://www.frontiersin.org/articles/10.3389/fmed.2022.989950/full

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