Efficient biosynthesis of creatine by whole-cell catalysis from guanidinoacetic acid in Corynebacterium glutamicum

Efficient biosynthesis of creatine by whole-cell catalysis from guanidinoacetic acid in Corynebacterium glutamicum

Creatine is a naturally occurring derivative of an amino acid commonly utilized in functional foods and pharmaceuticals. Nevertheless, the current industrial synthesis of creatine relies on chemical processes, which may hinder its utilization in certain applications. Therefore, a biological approach...

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Bibliographic Details
Main Authors: Chunjian Li, Pengdong Sun, Guoqing Wei, Yuqi Zhu, Jingyuan Li, Yanfeng Liu, Jian Chen, Yang Deng
Format: Article
Language:English
Published: KeAi Communications Co., Ltd. 2024-03-01
Series:Synthetic and Systems Biotechnology
Subjects:
Creatine
Corynebacterium glutamicum
Whole-cell biocatalysis
Guanidinoacetate N-Methyltransferase
Food additive
Online Access:http://www.sciencedirect.com/science/article/pii/S2405805X24000036

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