Antioxidative Properties of Colpomenia sinuosa Organic Extract

Background and purpose: Free radicals play an important role in development of various diseases and anti-oxidant compounds could be of great benefit in prevention and treatment of these diseases. Today, natural antioxidants are more safe and healthier than synthetic ones and are not limited to terre...

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Main Authors: Ali Taheri, Sajjad Moradi
Format: Article
Language:English
Published: Mazandaran University of Medical Sciences 2018-05-01
Series:Journal of Mazandaran University of Medical Sciences
Subjects:
Online Access:http://jmums.mazums.ac.ir/article-1-7568-en.html
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author Ali Taheri
Sajjad Moradi
author_facet Ali Taheri
Sajjad Moradi
author_sort Ali Taheri
collection DOAJ
description Background and purpose: Free radicals play an important role in development of various diseases and anti-oxidant compounds could be of great benefit in prevention and treatment of these diseases. Today, natural antioxidants are more safe and healthier than synthetic ones and are not limited to terrestrial resources of marine. Algae are found to be rich in antioxidant compounds and this study aimed at examining the antioxidant properties of Colpomenia sinuosa obtained from Chabahar coasts. Materials and methods: Extraction was performed using 95% methanol. DPPH free radical scavenging, the activity and reducing power chelated Fe (II) ions were tested in 1, 0.1, and 0.01 mg/ml of the extract. Results: The highest rates of free radical scavenging DPPH, activity and reducing power chelated Fe (II) ions, were 55.45±1.25%, 90.11±2.83%, and 0.06± 0.01 at 1 mg/ml, respectively. Conclusion: The methanolic extract of Colpomenia sinuosa showed good antioxidant properties, especially the type II antioxidants and can be used as supplement or medication after being approved in preclinical and clinical studies.
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spelling doaj.art-b5e97f715c99411891d52a9f22869bdb2023-01-25T07:35:17ZengMazandaran University of Medical SciencesJournal of Mazandaran University of Medical Sciences1735-92601735-92792018-05-0128160151155Antioxidative Properties of Colpomenia sinuosa Organic ExtractAli Taheri0Sajjad Moradi1 Background and purpose: Free radicals play an important role in development of various diseases and anti-oxidant compounds could be of great benefit in prevention and treatment of these diseases. Today, natural antioxidants are more safe and healthier than synthetic ones and are not limited to terrestrial resources of marine. Algae are found to be rich in antioxidant compounds and this study aimed at examining the antioxidant properties of Colpomenia sinuosa obtained from Chabahar coasts. Materials and methods: Extraction was performed using 95% methanol. DPPH free radical scavenging, the activity and reducing power chelated Fe (II) ions were tested in 1, 0.1, and 0.01 mg/ml of the extract. Results: The highest rates of free radical scavenging DPPH, activity and reducing power chelated Fe (II) ions, were 55.45±1.25%, 90.11±2.83%, and 0.06± 0.01 at 1 mg/ml, respectively. Conclusion: The methanolic extract of Colpomenia sinuosa showed good antioxidant properties, especially the type II antioxidants and can be used as supplement or medication after being approved in preclinical and clinical studies.http://jmums.mazums.ac.ir/article-1-7568-en.htmlantioxidantfree radicalseaweedreduction powerchelating activity
spellingShingle Ali Taheri
Sajjad Moradi
Antioxidative Properties of Colpomenia sinuosa Organic Extract
Journal of Mazandaran University of Medical Sciences
antioxidant
free radical
seaweed
reduction power
chelating activity
title Antioxidative Properties of Colpomenia sinuosa Organic Extract
title_full Antioxidative Properties of Colpomenia sinuosa Organic Extract
title_fullStr Antioxidative Properties of Colpomenia sinuosa Organic Extract
title_full_unstemmed Antioxidative Properties of Colpomenia sinuosa Organic Extract
title_short Antioxidative Properties of Colpomenia sinuosa Organic Extract
title_sort antioxidative properties of colpomenia sinuosa organic extract
topic antioxidant
free radical
seaweed
reduction power
chelating activity
url http://jmums.mazums.ac.ir/article-1-7568-en.html
work_keys_str_mv AT alitaheri antioxidativepropertiesofcolpomeniasinuosaorganicextract
AT sajjadmoradi antioxidativepropertiesofcolpomeniasinuosaorganicextract