Increased Levels of Chitotriosidase and YKL-40 in Cerebrospinal Fluid from Patients with Alzheimer's Disease

Increased Levels of Chitotriosidase and YKL-40 in Cerebrospinal Fluid from Patients with Alzheimer's Disease

Background: The cerebrospinal fluid (CSF) biomarkers total tau, abnormally phosphorylated tau and amyloid β 1-42 are strongly associated with Alzheimer's disease (AD). Apart from the pathologic hallmarks that these biomarkers represent, other processes such as inflammation and microglial activa...

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Bibliographic Details
Main Authors: Christoffer Rosén, Carl-Henrik Andersson, Ulf Andreasson, José L. Molinuevo, Maria Bjerke, Lorena Rami, Albert Lladó, Kaj Blennow, Henrik Zetterberg
Format: Article
Language:English
Published: Karger Publishers 2014-07-01
Series:Dementia and Geriatric Cognitive Disorders Extra
Subjects:
Cerebrospinal fluid
Alzheimer’s disease
Biomarkers
Inflammation
Online Access:http://www.karger.com/Article/FullText/362164

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