Update on the Angiotensin Converting Enzyme 2-Angiotensin (1-7)-Mas Receptor Axis: Fetal Programming, Sex Differences and Intracellular Pathways

Update on the Angiotensin Converting Enzyme 2-Angiotensin (1-7)-Mas Receptor Axis: Fetal Programming, Sex Differences and Intracellular Pathways

The renin-angiotensin-system (RAS) constitutes an important hormonal system in the physiological regulation of blood pressure. Indeed, dysregulation of the RAS may lead to the development of cardiovascular pathologies including kidney injury. Moreover, the blockade of this system by the inhibition...

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Bibliographic Details
Main Authors: Mark C. Chappell, Allyson C. Marshall, Ebaa M. Alzayadneh, Hossam A Shaltout, Debra I. Diz
Format: Article
Language:English
Published: Frontiers Media S.A. 2014-01-01
Series:Frontiers in Endocrinology
Subjects:
Hypertension
fetal programming
Angiotensin-(1-7)
ACE2
ACE
Online Access:http://journal.frontiersin.org/Journal/10.3389/fendo.2013.00201/full

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