TECHNETIUM-99M MIBI GATED MYOCARDIAL PERFUSION SINGLE PHOTON EMISSION COMPUTED TOMOGRAPHY IMAGING – VALIDATION OF STRESS ONLY PROTOCOL
Objective: To validate ‘stress only’ protocol against ‘rest stress protocol in normal and essentially normal cases undergoing Tc99m MIBI gated myocardial perfusion Single Photon Emission Computed Tomography imaging. Study Design: A retrospective observational study. Place and Duration of Study...
| Main Authors: | , , , |
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| Format: | Article |
| Language: | English |
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Army Medical College Rawalpindi
2021-10-01
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| Series: | Pakistan Armed Forces Medical Journal |
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| Online Access: | https://www.pafmj.org/index.php/PAFMJ/article/view/5391/3612 |
| _version_ | 1818844288405995520 |
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| author | Zaigham Salim Dar Mehdi Raza Muhammad Atif Aown Raza Bukhari |
| author_facet | Zaigham Salim Dar Mehdi Raza Muhammad Atif Aown Raza Bukhari |
| author_sort | Zaigham Salim Dar |
| collection | DOAJ |
| description | Objective: To validate ‘stress only’ protocol against ‘rest stress protocol in normal and essentially normal cases undergoing Tc99m MIBI gated myocardial perfusion Single Photon Emission Computed Tomography imaging.
Study Design: A retrospective observational study.
Place and Duration of Study: Department of Nuclear Cardiology, Armed Forces Institute of Cardiology/National Institute of Heart Disease, Rawalpindi, Pakistan, from Jul to Sep 2019.
Methodology: 136 cases were included. Patients underwent Tc-99m gated Single Photon Emission Computed Tomography MPI using a single day, rest/stress protocol. The rest study was performed first with 8-10 mCi Tc-99m MIBI followed by stress study, 3 hours later with 3 times the rest dose. The most common stress technique was pharmacological stress and bicycle ergometer exercise with 0.14 mg/kg/min adenosine infusion. Few patients underwent physical stress using Bruce protocol, achieving a minimum of 85% of the target heart rate. Mages–stress followed by rest–were evaluated by two experienced nuclear cardiologists (blinded to the MPI reports) and interpreted as ‘normal’ or ‘essentially normal’.
Results: Evaluation of stress-only and rest-stress Single Photon Emission Computed Tomography myocardial images yielded a concordance rate of 84.56% with Cohen’s kappa coefficient of 0.69.
Conclusion: Substantial agreement and good concordance were found in normal and essentially normal ‘stress only’ and ‘rest stress protocols. |
| first_indexed | 2024-12-19T05:11:23Z |
| format | Article |
| id | doaj.art-b5f02dee2c2d4c2fa352da4ad829766e |
| institution | Directory Open Access Journal |
| issn | 0030-9648 2411-8842 |
| language | English |
| last_indexed | 2024-12-19T05:11:23Z |
| publishDate | 2021-10-01 |
| publisher | Army Medical College Rawalpindi |
| record_format | Article |
| series | Pakistan Armed Forces Medical Journal |
| spelling | doaj.art-b5f02dee2c2d4c2fa352da4ad829766e2022-12-21T20:34:47ZengArmy Medical College RawalpindiPakistan Armed Forces Medical Journal0030-96482411-88422021-10-0171517411745TECHNETIUM-99M MIBI GATED MYOCARDIAL PERFUSION SINGLE PHOTON EMISSION COMPUTED TOMOGRAPHY IMAGING – VALIDATION OF STRESS ONLY PROTOCOLZaigham Salim Dar0Mehdi Raza1Muhammad Atif2Aown Raza Bukhari3Armed Forces Institute of Cardiology/National University of Medical Sciences (NUMS) Rawalpindi PakistanArmed Forces Institute of Cardiology/National University of Medical Sciences (NUMS) Rawalpindi PakistanArmed Forces Institute of Cardiology/National University of Medical Sciences (NUMS) Rawalpindi PakistanArmed Forces Institute of Cardiology/National University of Medical Sciences (NUMS) Rawalpindi PakistanObjective: To validate ‘stress only’ protocol against ‘rest stress protocol in normal and essentially normal cases undergoing Tc99m MIBI gated myocardial perfusion Single Photon Emission Computed Tomography imaging. Study Design: A retrospective observational study. Place and Duration of Study: Department of Nuclear Cardiology, Armed Forces Institute of Cardiology/National Institute of Heart Disease, Rawalpindi, Pakistan, from Jul to Sep 2019. Methodology: 136 cases were included. Patients underwent Tc-99m gated Single Photon Emission Computed Tomography MPI using a single day, rest/stress protocol. The rest study was performed first with 8-10 mCi Tc-99m MIBI followed by stress study, 3 hours later with 3 times the rest dose. The most common stress technique was pharmacological stress and bicycle ergometer exercise with 0.14 mg/kg/min adenosine infusion. Few patients underwent physical stress using Bruce protocol, achieving a minimum of 85% of the target heart rate. Mages–stress followed by rest–were evaluated by two experienced nuclear cardiologists (blinded to the MPI reports) and interpreted as ‘normal’ or ‘essentially normal’. Results: Evaluation of stress-only and rest-stress Single Photon Emission Computed Tomography myocardial images yielded a concordance rate of 84.56% with Cohen’s kappa coefficient of 0.69. Conclusion: Substantial agreement and good concordance were found in normal and essentially normal ‘stress only’ and ‘rest stress protocols.https://www.pafmj.org/index.php/PAFMJ/article/view/5391/3612myocardial perfusion imagingrest/stress imaging |
| spellingShingle | Zaigham Salim Dar Mehdi Raza Muhammad Atif Aown Raza Bukhari TECHNETIUM-99M MIBI GATED MYOCARDIAL PERFUSION SINGLE PHOTON EMISSION COMPUTED TOMOGRAPHY IMAGING – VALIDATION OF STRESS ONLY PROTOCOL Pakistan Armed Forces Medical Journal myocardial perfusion imaging rest/stress imaging |
| title | TECHNETIUM-99M MIBI GATED MYOCARDIAL PERFUSION SINGLE PHOTON EMISSION COMPUTED TOMOGRAPHY IMAGING – VALIDATION OF STRESS ONLY PROTOCOL |
| title_full | TECHNETIUM-99M MIBI GATED MYOCARDIAL PERFUSION SINGLE PHOTON EMISSION COMPUTED TOMOGRAPHY IMAGING – VALIDATION OF STRESS ONLY PROTOCOL |
| title_fullStr | TECHNETIUM-99M MIBI GATED MYOCARDIAL PERFUSION SINGLE PHOTON EMISSION COMPUTED TOMOGRAPHY IMAGING – VALIDATION OF STRESS ONLY PROTOCOL |
| title_full_unstemmed | TECHNETIUM-99M MIBI GATED MYOCARDIAL PERFUSION SINGLE PHOTON EMISSION COMPUTED TOMOGRAPHY IMAGING – VALIDATION OF STRESS ONLY PROTOCOL |
| title_short | TECHNETIUM-99M MIBI GATED MYOCARDIAL PERFUSION SINGLE PHOTON EMISSION COMPUTED TOMOGRAPHY IMAGING – VALIDATION OF STRESS ONLY PROTOCOL |
| title_sort | technetium 99m mibi gated myocardial perfusion single photon emission computed tomography imaging validation of stress only protocol |
| topic | myocardial perfusion imaging rest/stress imaging |
| url | https://www.pafmj.org/index.php/PAFMJ/article/view/5391/3612 |
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